Burr Jamie F, Drury C Taylor, Phillips Aaron A, Ivey Adam, Ku Jerry, Warburton Darren E R
University of British Columbia, Vancouver Canada, Cardiovascular Physiology and Rehabilitation Laboratory, Physical Activity and Chronic Disease Prevention Unit, Canada; Human Performance and Health Laboratory, University of PEI, Charlottetown, Canada.
University of British Columbia, Vancouver Canada, Cardiovascular Physiology and Rehabilitation Laboratory, Physical Activity and Chronic Disease Prevention Unit, Canada; Experimental Medicine Program, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
J Sci Med Sport. 2014 May;17(3):322-5. doi: 10.1016/j.jsams.2013.04.018. Epub 2013 May 22.
Recent reports that habitual marathon runners demonstrate higher levels of stiffness and cardiovascular risk factors have been of great interest to the medical and scientific community. Ultra-marathon running, that is any distance >42.2 km, is increasing in popularity; however, little is known regarding the physiological effects of the sport's unique training and racing practices on vascular health.
To characterize and compare the arterial compliance of male long-term (>5 years) ultra-marathoners with recreationally active controls, and examine the associations of training related practices with systemic arterial compliance.
We employed a case-control comparison design using long-term habitual ultra-marathon runners (n=18) and an age matched cohort of normative recreationally active males.
Arterial compliance was measured at rest using radial applanation tonometry (CR-2000, HDI) for diastolic pulse contour analysis. Compliance was compared with normative data, participant characteristics, and associated exercise parameters.
In representative ultra-endurance runners, large artery compliance of long-term participants was reduced compared with physically active age-matched controls (p=0.03) and is related to select training variables. Specifically, in a representative subset for whom we obtained detailed training data, decreased compliance was related to longer typical running distance per training session (r=-0.72, p=0.03); however, more broad definitions of frequency, intensity, and duration revealed no association for the runners as a whole.
Given the known associations of arterial stiffness with future cardiovascular events, ultra-endurance runners may be at an increased risk of a cardiovascular event compared with their normally active counterparts.
最近有报道称，习惯性马拉松跑者表现出更高的僵硬程度和心血管危险因素水平，这引起了医学界和科学界的极大兴趣。超级马拉松跑，即任何超过42.2公里的距离，正越来越受欢迎；然而，关于这项运动独特的训练和比赛方式对血管健康的生理影响，人们知之甚少。
对长期（>5年）参加超级马拉松的男性与有休闲运动习惯的对照组的动脉顺应性进行特征描述和比较，并研究与训练相关的行为与全身动脉顺应性之间的关联。
我们采用了病例对照比较设计，纳入长期习惯性参加超级马拉松的跑者（n = 18）以及年龄匹配的有休闲运动习惯的正常男性队列。
使用桡动脉压平式眼压计（CR - 2000，HDI）在静息状态下测量动脉顺应性，用于舒张期脉搏轮廓分析。将顺应性与标准数据、参与者特征及相关运动参数进行比较。
在代表性的超级耐力跑者中，长期参与者的大动脉顺应性低于年龄匹配的有体育活动习惯的对照组（p = 0.03），且与特定训练变量有关。具体而言，在我们获取了详细训练数据的代表性子集中，顺应性降低与每次训练的典型跑步距离较长有关（r = -0.72，p = 0.03）；然而，对频率、强度和持续时间的更广泛定义显示，对于整体跑者而言并无关联。
鉴于已知动脉僵硬与未来心血管事件之间的关联，与正常活动的同龄人相比
