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墨西哥恰帕斯州和瓦哈卡州儿童(血液和尿液样本)中的滴滴涕、滴滴伊和 1-羟基芘水平。

DDT, DDE, and 1-hydroxypyrene levels in children (in blood and urine samples) from Chiapas and Oaxaca, Mexico.

机构信息

Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Avenida Sierra Leona No. 550, Colonia Lomas Segunda Sección, San Luis Potosí, 78210, SLP, México,

出版信息

Environ Monit Assess. 2013 Nov;185(11):9287-93. doi: 10.1007/s10661-013-3251-y. Epub 2013 May 25.

Abstract

The aim of this study was to evaluate the DDT, DDE, and 1-hydroxypyrene exposure levels of children living in communities located in southeastern Mexico. The study communities were Lacanja and Victoria in Chiapas state and Ventanilla in Oaxaca state. Children living in Lacanja had total blood DDT levels (mean ± SD, 29,039.6 ± 11,261.4 ng/g lipid) that were significantly higher than those of children in Victoria (10,220.5 ± 7,893.1 ng/g lipid) and Ventanilla (11,659.7 ± 6,683.7 ng/g lipid). With respect to the 1-hydroxypyrene levels in urine samples, the levels in Lacanja (4.8 ± 4.1 μg/L or 4.5 ± 3.9 μmol/mol creatinine) and Victoria (4.6 ± 3.8 μg/L or 3.9 ± 3.0 μmol/mol Cr) were significantly higher than levels found in Ventanilla (3.6 ± 1.4 μg/L or 2.5 ± 0.5 μmol/mol Cr). In conclusion, our data indicate high levels of exposure in children living in the communities studied in this work. The evidence found in this study could be further used as a trigger to revisit local policies on environmental exposures.

摘要

本研究旨在评估生活在墨西哥东南部社区的儿童的滴滴涕、滴滴伊和 1-羟基芘的暴露水平。研究社区位于恰帕斯州的拉坎哈和维多利亚州以及瓦亚塔港。居住在拉坎哈的儿童的全血滴滴涕水平(均值±SD,29039.6±11261.4ng/g 脂质)明显高于维多利亚州(10220.5±7893.1ng/g 脂质)和瓦亚塔港(11659.7±6683.7ng/g 脂质)的儿童。就尿液样本中的 1-羟基芘水平而言,拉坎哈(4.8±4.1μg/L 或 4.5±3.9μmol/mol 肌酐)和维多利亚州(4.6±3.8μg/L 或 3.9±3.0μmol/mol Cr)的水平明显高于瓦亚塔港(3.6±1.4μg/L 或 2.5±0.5μmol/mol Cr)。总之,我们的数据表明,在本研究中,生活在这些社区的儿童暴露水平较高。本研究中发现的证据可以进一步作为重新审查当地环境暴露政策的触发因素。

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