Department of Biology, Stanford University, Stanford, CA 94305, USA.
Genetics. 2013 Aug;194(4):1037-9. doi: 10.1534/genetics.113.152181. Epub 2013 May 24.
SLiM is an efficient forward population genetic simulation designed for studying the effects of linkage and selection on a chromosome-wide scale. The program can incorporate complex scenarios of demography and population substructure, various models for selection and dominance of new mutations, arbitrary gene structure, and user-defined recombination maps.
SLiM 是一款高效的正向群体遗传模拟程序,专门用于研究连锁和选择对染色体范围的影响。该程序可以纳入复杂的人口统计学和群体亚结构情景、新突变的选择和显性的各种模型、任意基因结构以及用户定义的重组图谱。