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SLiM:通过选择和连锁模拟进化。

SLiM: simulating evolution with selection and linkage.

机构信息

Department of Biology, Stanford University, Stanford, CA 94305, USA.

出版信息

Genetics. 2013 Aug;194(4):1037-9. doi: 10.1534/genetics.113.152181. Epub 2013 May 24.

Abstract

SLiM is an efficient forward population genetic simulation designed for studying the effects of linkage and selection on a chromosome-wide scale. The program can incorporate complex scenarios of demography and population substructure, various models for selection and dominance of new mutations, arbitrary gene structure, and user-defined recombination maps.

摘要

SLiM 是一款高效的正向群体遗传模拟程序,专门用于研究连锁和选择对染色体范围的影响。该程序可以纳入复杂的人口统计学和群体亚结构情景、新突变的选择和显性的各种模型、任意基因结构以及用户定义的重组图谱。

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