• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

揭示超分辨率显微镜数据中隐藏的新特征。

Unraveling novel features hidden in superresolution microscopy data.

作者信息

Holcman David

机构信息

Ecole Normale Supérieure; Institute for Biology; IBENS; Group of Computational Biology and Applied Mathematics; Paris, France.

出版信息

Commun Integr Biol. 2013 May 1;6(3):e23893. doi: 10.4161/cib.23893.

DOI:10.4161/cib.23893
PMID:23710279
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3656019/
Abstract

Stochastic analysis of superresolution microscopy data obtained from receptor trafficking on neurons reveals novel organized molecular assembly generating long range forces. Would that have been possible with single particle tracking? How have we characterized these molecular assemblies?

摘要

对从神经元上受体运输获得的超分辨率显微镜数据进行随机分析，揭示了产生长程力的新型有组织分子组装。单粒子追踪能做到这一点吗？我们如何表征这些分子组装？

相似文献

1
Unraveling novel features hidden in superresolution microscopy data.揭示超分辨率显微镜数据中隐藏的新特征。
Commun Integr Biol. 2013 May 1;6(3):e23893. doi: 10.4161/cib.23893.
2
Analysis and Interpretation of Superresolution Single-Particle Trajectories.超分辨率单粒子轨迹的分析与解读
Biophys J. 2015 Nov 3;109(9):1761-71. doi: 10.1016/j.bpj.2015.09.003.
3
A Quantitative Live-Cell Superresolution Imaging Framework for Measuring the Mobility of Single Molecules at Sites of Virus Assembly.一种用于测量病毒组装位点单分子流动性的定量活细胞超分辨率成像框架。
Pathogens. 2020 Nov 21;9(11):972. doi: 10.3390/pathogens9110972.
4
Residence times of receptors in dendritic spines analyzed by stochastic simulations in empirical domains.通过经验域中的随机模拟分析树突棘中受体的驻留时间。
Biophys J. 2014 Dec 16;107(12):3008-3017. doi: 10.1016/j.bpj.2014.10.018.
5
Heterogeneity of AMPA receptor trafficking and molecular interactions revealed by superresolution analysis of live cell imaging.活细胞成像的超分辨率分析揭示了 AMPA 受体转运和分子相互作用的异质性。
Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17052-7. doi: 10.1073/pnas.1204589109. Epub 2012 Oct 3.
6
Recovering a stochastic process from super-resolution noisy ensembles of single-particle trajectories.从单粒子轨迹的超分辨率噪声集合中恢复随机过程。
Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Nov;92(5):052109. doi: 10.1103/PhysRevE.92.052109. Epub 2015 Nov 9.
7
Stochastic approach to the molecular counting problem in superresolution microscopy.超分辨率显微镜中分子计数问题的随机方法。
Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):E110-8. doi: 10.1073/pnas.1408071112. Epub 2014 Dec 22.
8
Answers to fundamental questions in superresolution microscopy.超分辨率显微镜中基本问题的答案。
Philos Trans A Math Phys Eng Sci. 2021 Jun 14;379(2199):20210105. doi: 10.1098/rsta.2021.0105. Epub 2021 Apr 26.
9
Three-Dimensional Superresolution Imaging of the FtsZ Ring during Cell Division of the Cyanobacterium .三维超分辨率成像研究蓝藻细胞分裂过程中的 FtsZ 环
mBio. 2017 Nov 21;8(6):e00657-17. doi: 10.1128/mBio.00657-17.
10
Widely accessible method for superresolution fluorescence imaging of living systems.用于活系统超分辨率荧光成像的广泛适用方法。
Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10909-14. doi: 10.1073/pnas.1204917109. Epub 2012 Jun 18.

引用本文的文献

1
High-throughput super-resolution single-particle trajectory analysis reconstructs organelle dynamics and membrane reorganization.高通量超分辨率单颗粒轨迹分析重建细胞器动力学和膜重排。
Cell Rep Methods. 2022 Aug 22;2(8):100277. doi: 10.1016/j.crmeth.2022.100277.
2
Biophysics of high density nanometer regions extracted from super-resolution single particle trajectories: application to voltage-gated calcium channels and phospholipids.从超高分辨率单颗粒轨迹中提取的高密度纳米区域的生物物理学：在电压门控钙通道和磷脂中的应用。
Sci Rep. 2019 Dec 11;9(1):18818. doi: 10.1038/s41598-019-55124-8.
3
Analysis and Interpretation of Superresolution Single-Particle Trajectories.超分辨率单粒子轨迹的分析与解读
Biophys J. 2015 Nov 3;109(9):1761-71. doi: 10.1016/j.bpj.2015.09.003.

本文引用的文献

1
Heterogeneity of AMPA receptor trafficking and molecular interactions revealed by superresolution analysis of live cell imaging.活细胞成像的超分辨率分析揭示了 AMPA 受体转运和分子相互作用的异质性。
Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17052-7. doi: 10.1073/pnas.1204589109. Epub 2012 Oct 3.
2
Narrow escape through a funnel and effective diffusion on a crowded membrane.通过漏斗的惊险逃脱以及在拥挤膜上的有效扩散。
Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Aug;84(2 Pt 1):021906. doi: 10.1103/PhysRevE.84.021906. Epub 2011 Aug 5.
3
Dynamic superresolution imaging of endogenous proteins on living cells at ultra-high density.活细胞中超高密度内源性蛋白质的动态超分辨率成像。
Biophys J. 2010 Aug 9;99(4):1303-10. doi: 10.1016/j.bpj.2010.06.005.
4
High-density mapping of single-molecule trajectories with photoactivated localization microscopy.利用光激活定位显微镜对单分子轨迹进行高密度映射。
Nat Methods. 2008 Feb;5(2):155-7. doi: 10.1038/nmeth.1176. Epub 2008 Jan 13.
5
Paradigm shift of the plasma membrane concept from the two-dimensional continuum fluid to the partitioned fluid: high-speed single-molecule tracking of membrane molecules.质膜概念从二维连续流体到分区流体的范式转变：膜分子的高速单分子追踪
Annu Rev Biophys Biomol Struct. 2005;34:351-78. doi: 10.1146/annurev.biophys.34.040204.144637.
6
AMPA receptor trafficking at excitatory synapses.AMPA受体在兴奋性突触处的转运。
Neuron. 2003 Oct 9;40(2):361-79. doi: 10.1016/s0896-6273(03)00640-8.
7
The role of receptor diffusion in the organization of the postsynaptic membrane.受体扩散在突触后膜组织中的作用。
Nat Rev Neurosci. 2003 Apr;4(4):251-65. doi: 10.1038/nrn1077.
8
Single-particle tracking: applications to membrane dynamics.单粒子追踪：在膜动力学中的应用
Annu Rev Biophys Biomol Struct. 1997;26:373-99. doi: 10.1146/annurev.biophys.26.1.373.
9
Confined lateral diffusion of membrane receptors as studied by single particle tracking (nanovid microscopy). Effects of calcium-induced differentiation in cultured epithelial cells.通过单粒子追踪（纳米视野显微镜）研究膜受体的受限侧向扩散。钙诱导培养上皮细胞分化的影响。
Biophys J. 1993 Nov;65(5):2021-40. doi: 10.1016/S0006-3495(93)81253-0.
10
Lateral movements of membrane glycoproteins restricted by dynamic cytoplasmic barriers.膜糖蛋白的侧向运动受到动态细胞质屏障的限制。
Science. 1991 Nov 29;254(5036):1379-82. doi: 10.1126/science.1835798.