在生命科学新革命的开端。
At the dawn of a new revolution in life sciences.
作者信息
Baluška František, Witzany Guenther
机构信息
František Baluška, IZMB, University of Bonn, 53113 Bonn, Germany.
出版信息
World J Biol Chem. 2013 May 26;4(2):13-5. doi: 10.4331/wjbc.v4.i2.13.
Abstract
In a recently published article Sydney Brenner argued that the most relevant scientific revolution in biology at his time was the breakthrough of the role of "information" in biology. The fundamental concept that integrates this new biological "information" with matter and energy is the universal Turing machine and von Neumann's self-reproducing machines. In this article we demonstrate that in contrast to Turing/von Neumann machines living cells can really reproduce themselves. Additionally current knowledge on the roles of non-coding RNAs indicates a radical violation of the central dogma of molecular biology and opens the way to a new revolution in life sciences.
摘要
在悉尼·布伦纳最近发表的一篇文章中，他认为当时生物学领域最具相关性的科学革命是“信息”在生物学中作用的突破。将这种新的生物学“信息”与物质和能量整合起来的基本概念是通用图灵机和冯·诺依曼的自我复制机器。在本文中，我们证明，与图灵/冯·诺依曼机器不同，活细胞能够真正实现自我复制。此外，目前关于非编码RNA作用的知识表明，这严重违背了分子生物学的中心法则，并为生命科学领域的一场新革命开辟了道路。
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