Harned Melanie S, Valenstein Helen R
Behavioral Research and Therapy Clinics, Department of Psychology, Box 355915, University of Washington Seattle, WA, 98195 USA.
F1000Prime Rep. 2013 May 1;5:15. doi: 10.12703/P5-15. Print 2013.
Anxiety disorders are highly prevalent among individuals with borderline personality disorder, with comorbidity rates of up to 90%. Anxiety disorders have been found to reduce the likelihood of achieving remission from borderline personality disorder over time and to increase the risk of suicide and self-injury in this population. Evidence-based treatments for borderline personality disorder have not sufficiently focused on targeting anxiety disorders, and their effects on these disorders are either limited or unknown. Conversely, evidence-based treatments for anxiety disorders typically exclude suicidal, self-injuring, and seriously comorbid patients, thereby limiting their generalizability to individuals with borderline personality disorder. To address these limitations, recent research has begun to emerge focused on developing and evaluating treatments for individuals with co-occurring borderline personality disorder and anxiety disorders, specifically posttraumatic stress disorder (PTSD), with promising initial results. However, there is a need for additional research in this area, particularly studies evaluating the treatment of anxiety disorders among high-risk and complex borderline personality disorder patients.
焦虑症在边缘性人格障碍患者中极为普遍，共病率高达90%。研究发现，焦虑症会降低边缘性人格障碍患者随时间实现缓解的可能性，并增加该人群自杀和自我伤害的风险。针对边缘性人格障碍的循证治疗尚未充分聚焦于针对焦虑症，其对这些障碍的效果要么有限，要么未知。相反，针对焦虑症的循证治疗通常将有自杀行为、自我伤害行为和严重共病的患者排除在外，从而限制了其对边缘性人格障碍患者的普遍适用性。为解决这些局限性，最近开始出现一些研究，专注于为同时患有边缘性人格障碍和焦虑症（特别是创伤后应激障碍）的个体开发和评估治疗方法，初步结果很有前景。然而，这一领域还需要更多研究，特别是评估高危和复杂边缘性人格障碍患者焦虑症治疗的研究。
