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边缘型人格障碍患者和轴 II 对照受试者 PTSD 的 10 年病程。

The 10-year course of PTSD in borderline patients and axis II comparison subjects.

机构信息

McLean Hospital, Belmont, MA 02478, USA.

出版信息

Acta Psychiatr Scand. 2011 Nov;124(5):349-56. doi: 10.1111/j.1600-0447.2011.01717.x. Epub 2011 May 12.

Abstract

OBJECTIVE

The first objective is to detail the prevalence of post-traumatic stress disorder (PTSD) over a decade of follow-up for those in both study groups. The second is to determine time-to-remission, recurrence, and new onset of PTSD, and the third is to assess the relationship between sexual adversity and the likelihood of remission and recurrence of PTSD.

METHOD

The SCID I was administered to 290 borderline in-patients and 72 axis II comparison subjects during their index admission and re-administered at five contiguous 2-year follow-up periods.

RESULTS

The prevalence of PTSD declined significantly over time for patients with borderline personality (BPD) (61%). Over 85% of borderline patients meeting criteria for PTSD at baseline experienced a remission by the time of the 10-year follow-up. Recurrences (40%) and new onsets (27%) were less common. A childhood history of sexual abuse significantly decreased the likelihood of remission from PTSD, and an adult history of sexual assault significantly increased the likelihood of a recurrence of PTSD.

CONCLUSION

Taken together, the results of this study suggest that PTSD is not a chronic disorder for the majority of borderline patients. They also suggest a strong relationship between sexual adversity and the course of PTSD among patients with BPD.

摘要

目的

第一项目的是详细说明在两个研究组的超过十年的随访中创伤后应激障碍(PTSD)的患病率。第二项目的是确定缓解、复发和新发病例的时间,第三项目的是评估性逆境与 PTSD 缓解和复发的可能性之间的关系。

方法

在指数住院期间,对 290 名边缘型住院患者和 72 名轴 II 对照组患者进行了 SCID I 诊断,并在连续的 5 个 2 年随访期间重新进行了诊断。

结果

边缘型人格障碍(BPD)患者的 PTSD 患病率随着时间的推移显著下降(61%)。超过 85%的在基线时符合 PTSD 标准的边缘型患者在 10 年随访时已经缓解。复发(40%)和新发病例(27%)较少见。童年时期的性虐待史显著降低了 PTSD 缓解的可能性,而成年时期的性侵犯史显著增加了 PTSD 复发的可能性。

结论

总的来说,这项研究的结果表明,对于大多数边缘型患者来说,PTSD 不是一种慢性疾病。它们还表明,性逆境与 BPD 患者 PTSD 病程之间存在很强的关系。

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