Falkenstern-Ge R F, Bode-Erdmann S, Ott G, Wohlleber M, Kohlhäufl M
Division of Pulmonology, Klinik Schillerhoehe, Center for Pulmonology and Thoracic Surgery, Teaching Hospital of the University of Tuebingen, Solitude Street 18, 70839 Gerlingen, Germany.
Case Rep Oncol Med. 2013;2013:167585. doi: 10.1155/2013/167585. Epub 2013 Apr 28.
Background. Sweat gland carcinoma is a rare malignancy with a high metastatic potential seen more commonly in elderly patients. The scalp is the most common site of occurrence and it usually spreads to regional lymph nodes. Liver, lungs, and bones are the most common sites of distant metastasis. Late lung metastasis of sweat gland adenocarcinoma after a time span of 5 years is extremely rare. Aim. We report a patient with late lung metastasis of a primary sweat gland carcinoma 10 years after initial surgical resection. Conclusion. Sweat gland carcinomas are rare cancers with a poor prognosis. Surgery in the form of wide local excision and lymph node dissection is the mainstay of treatment. Late pulmonary metastases with a latency of 10 years have never been reported in the literature. This is the first clinical documentation of late lung metastasis from sweat gland carcinoma with a latency period of 10 years.
背景。汗腺癌是一种罕见的恶性肿瘤,具有较高的转移潜能,多见于老年患者。头皮是最常见的发病部位,通常会转移至区域淋巴结。肝脏、肺和骨骼是最常见的远处转移部位。原发性汗腺腺癌在5年后发生晚期肺转移极为罕见。目的。我们报告一例患者,在初次手术切除10年后发生原发性汗腺癌的晚期肺转移。结论。汗腺癌是预后较差的罕见癌症。广泛局部切除和淋巴结清扫形式的手术是主要治疗方法。文献中从未报道过潜伏期为10年的晚期肺转移。这是首例潜伏期为10年的汗腺癌晚期肺转移的临床记录。