Kumar Shree, Alfaadhel Talal, Albugami Meteb M
Department of Medicine, Division of Nephrology, Dalhousie University, Halifax, NS, Canada B3H 1V7.
Case Rep Transplant. 2013;2013:493516. doi: 10.1155/2013/493516. Epub 2013 Apr 28.
Infections remain a dreadful complication after solid organ transplantation. Almost all microorganisms could cause this complication, including unusual ones. We report a 73-year-old patient, with a history of kidney transplant for 38 years on minimum immunosuppression, who presented with high-grade fever and gastrointestinal symptoms. Klebsiella ozaenae was isolated from blood cultures. She had a prompt response to antibiotics and recovered completely in a short period. Subsequent evaluation of her nasal cavity and sinuses did not show any abnormalities. Klebsiella ozaenae is primarily a colonizer of the oral and nasopharyngeal mucosa, which does not usually cause severe infections. Only 12 cases of Klebsiella ozaenae bacteremia have been reported, none of them in the context of solid organ transplant recipient.
感染仍然是实体器官移植后一种可怕的并发症。几乎所有微生物都可能导致这种并发症，包括不常见的微生物。我们报告一名73岁患者，有38年肾移植病史，使用最低剂量免疫抑制剂，出现高热和胃肠道症状。从血培养中分离出鼻硬结克雷伯菌。她对抗生素反应迅速，短期内完全康复。随后对她的鼻腔和鼻窦进行评估未发现任何异常。鼻硬结克雷伯菌主要是口腔和鼻咽黏膜的定植菌，通常不会引起严重感染。仅报告过12例鼻硬结克雷伯菌血症病例，实体器官移植受者中均未出现过此类病例。
