Silchar Medical College and Hospital, Silchar, India.
Psychopathology. 2014;47(1):32-8. doi: 10.1159/000348486. Epub 2013 May 22.
BACKGROUND/AIMS: Through conceptualising poor insight in psychotic disorders as a form of anosognosia, frontal lobe dysfunction is often ascribed a vital role in its pathogenesis. The objective of this study was to compare the relation of insight in patients with psychotic illness to that of psychopathology and frontal lobe function.
Forty patients with psychotic disorder were selected from those attending the Department of Psychiatry in a tertiary care teaching hospital. The evaluation of insight was carried out using the Schedule for Assessment of Insight (SAI), that of frontal lobe function by the Frontal Assessment Battery (FAB) and psychopathology by the Brief Psychiatric Rating Scale (BPRS). The correlation coefficients were determined.
A negative correlation between SAI and BPRS scores means that the BPRS score is opposite to SAI scores. When the SAI total score was compared with the FAB total score, the correlation coefficient demonstrated a positive correlation. Better insight predicted lesser psychopathology and also that poor insight would exist with greater psychopathology. Better insight predicted a higher functional status of frontal lobes and prefrontal cortex in particular.
Insight deficits in schizophrenia and other psychotic illnesses are multidimensional. Integration of different aetiological factors like biological, psychopathological, environmental ones and others are necessary for a better understanding of insight in psychosis.
背景/目的：通过将精神病性障碍中的洞察力缺失概念化为一种否认症，额叶功能障碍通常被认为在其发病机制中起着至关重要的作用。本研究的目的是比较精神病患者的洞察力与精神病理学和额叶功能的关系。
从三级教学医院精神科就诊的精神病患者中选择 40 名患者。使用洞察力评估量表（SAI）评估洞察力，使用额叶评估量表（FAB）评估额叶功能，使用简明精神病评定量表（BPRS）评估精神病理学。确定相关系数。
SAI 与 BPRS 评分呈负相关，这意味着 BPRS 评分与 SAI 评分相反。当 SAI 总分与 FAB 总分进行比较时，相关系数显示出正相关。更好的洞察力预示着较少的精神病理学，也预示着较差的洞察力将伴随着更多的精神病理学。更好的洞察力预示着额叶和前额叶皮层的功能状态更高。
精神分裂症和其他精神病性障碍中的洞察力缺陷是多维度的。整合生物、精神病理学、环境等不同病因因素对于更好地理解精神病中的洞察力是必要的。
