School of Immunity and Infection, University of Birmingham Medical School, Birmingham, UK.
Hematol Oncol Clin North Am. 2013 Jun;27(3):411-41. doi: 10.1016/j.hoc.2013.03.003.
Platelet function tests have been traditionally used to aid in the diagnosis and management of patients with bleeding problems. Given the role of platelets in atherothrombosis, several dedicated platelet function instruments are now available that are simple to use and can be used as point-of-care assays. These can provide rapid assessment of platelet function within whole blood without the requirement of sample processing. Some tests can be used to monitor antiplatelet therapy and assess risk of bleeding and thrombosis, although current guidelines advise against this. This article discusses the potential utility of tests/instruments that are available.
血小板功能检测一直被用于辅助诊断和治疗出血问题的患者。鉴于血小板在动脉血栓形成中的作用,现在已经有几种专门的血小板功能仪器可供使用,这些仪器易于使用,可作为即时检测方法。这些方法可以在不进行样品处理的情况下,快速评估全血中的血小板功能。一些检测方法可用于监测抗血小板治疗和评估出血和血栓形成的风险,尽管目前的指南不建议这样做。本文讨论了现有的检测/仪器的潜在应用价值。