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实体器官移植受者的寄生虫感染。

Parasitic infections in solid organ transplant recipients.

机构信息

Department of Infectious Diseases, Georgetown University Hospital, Washington, DC 20007, USA.

出版信息

Infect Dis Clin North Am. 2013 Jun;27(2):395-427. doi: 10.1016/j.idc.2013.02.008. Epub 2013 Mar 29.

DOI:10.1016/j.idc.2013.02.008
PMID:23714347
Abstract

Parasitic diseases are rare infections after a solid organ transplant (SOT). Toxoplasmosis, Trypanosoma cruzi, and visceral leishmanias are the 3 main opportunistic protozoal infections that have the potential to be lethal if not diagnosed early and treated appropriately after SOT. Strongyloides stercoralis is the one helminthic disease that is life-threatening after transplant. This review addresses modes of transmission, methods of diagnosis, and treatment of the most serious parasitic infections in SOT. The role of targeted pretransplant screening of the donor and recipient for parasitic diseases is also discussed.

摘要

寄生虫病是实体器官移植（SOT）后的罕见感染。弓形虫病、克氏锥虫和内脏利什曼病是 3 种主要的机会性原生动物感染，如果在 SOT 后不能早期诊断和适当治疗，有可能致命。粪类圆线虫是移植后威胁生命的唯一一种寄生虫病。本文讨论了 SOT 中最严重的寄生虫感染的传播方式、诊断方法和治疗方法。还讨论了对供体和受者进行寄生虫病靶向移植前筛查的作用。

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