基因组测序揭示疟疾寄生虫中新出现的耐药性。
Genome sequencing sheds light on emerging drug resistance in malaria parasites.
机构信息
Broad Institute, Cambridge, Massachusetts, USA.
出版信息
Nat Genet. 2013 Jun;45(6):589-90. doi: 10.1038/ng.2648.
DOI:10.1038/ng.2648
PMID:23715326
Abstract
Plasmodium falciparum in Southeast Asia are gradually becoming resistant to artemesinin, a standard first-line treatment for malaria. Whole-genome sequencing offers a chance to better understand and perhaps undermine the parasite's evolutionary response to this drug.
摘要
东南亚的恶性疟原虫对青蒿素的耐药性逐渐增强，青蒿素是治疗疟疾的标准一线药物。全基因组测序为更好地理解并可能破坏寄生虫对这种药物的进化反应提供了机会。
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