含白藜芦醇的虎杖对职业男篮运动员炎症的影响。
Effects of polygonum cuspidatum containing resveratrol on inflammation in male professional basketball players.
作者信息
Zahedi Hoda Sadat, Jazayeri Shima, Ghiasvand Reza, Djalali Mahmoud, Eshraghian Mohammad Reza
机构信息
Department of Clinical Nutrition, School of Nutrition and Dietetics, Tehran University of Medical Sciences, Iran ; Department of Nutrition and Biochemistry, School of Public Health, Tehran University of Medical Sciences, Iran.
出版信息
Int J Prev Med. 2013 Apr;4(Suppl 1):S1-4.
Abstract
BACKGROUND
Exercise can lead to acute oxidative stress, which can result in oxidative damage and induce inflammation. Resveratrol may reduce the levels of inflammatory cytokines. Thus, we investigated the effects of this compound on the plasma levels of tumor necrosis factor-α (TNF-α) and interleukin 6 (IL-6) in male professional basketball players.
METHODS
Twenty healthy male professional basketball players were randomized into two groups (10 each). For 6 weeks, they received daily either 200 mg of polygonum cuspidatum extract (PCE) standardized to contain 20% trans-resveratrol equivalent to 40 mg trans-resveratrol or placebo. Indices of inflammation were measured before and after 6 weeks of supplementation.
RESULTS
There was a significant reduction in plasma levels of TNF-a and IL-6 after 6 weeks of supplementation; while no change was observed in these markers in the control group.
CONCLUSIONS
Present study shows that 6 weeks of PCE containing resveratrol supplementation reduces the inflammation in male professional basketball players.
摘要
背景
运动可导致急性氧化应激，进而造成氧化损伤并引发炎症。白藜芦醇可能会降低炎性细胞因子水平。因此，我们研究了该化合物对男性职业篮球运动员血浆肿瘤坏死因子-α（TNF-α）和白细胞介素6（IL-6）水平的影响。
方法
将20名健康男性职业篮球运动员随机分为两组（每组10人）。为期6周的时间里，他们每天分别服用200毫克虎杖提取物（PCE），该提取物经标准化处理，含有20%的反式白藜芦醇，相当于40毫克反式白藜芦醇，或服用安慰剂。在补充6周前后测量炎症指标。
结果
补充6周后，血浆TNF-α和IL-6水平显著降低；而对照组这些指标未发生变化。
结论
本研究表明，连续6周补充含白藜芦醇的PCE可减轻男性职业篮球运动员的炎症反应。
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