Ziółkowska Magdalena, Bień Stanisław, Okła Sławomir, Zyłka Stanisław
Dział Kliniczny Otolaryngologii Chirurgii Głowy i Szyi Świętokrzyskiego Centrum Onkologii w Kielcach, Kielce, Poland.
Otolaryngol Pol. 2013 May-Jun;67(3):154-63. doi: 10.1016/j.otpol.2013.03.002. Epub 2013 Mar 7.
The epidemiological data concerning the rare group of tumors derived from salivary glands recorded in the National Cancer Registry is insufficient because it records only malignant salivary glands tumors.
The epidemiological and clinical characteristics of 699 patients with salivary glands tumors (n=705).
The data were retrieved from ENT Department District Hospital in Kielce (01.09.1989-28.02.2001) and from Department of Otolaryngology Head and Neck Surgery Holy Cross Cancer Centre in Kielce (01.03.2001-31.12.2008).
In the analyzed group of 699 patients with 705 salivary glands tumors women predominated, consisting 54,2% of all group. The average age in group of malignant tumors was higher than in nonmalignant group. The risk of malignant neoplasms development increased with patient age. In the analyzed group of 705 salivary glands tumors the nonmalignant neoplasms dominated-78,3%. Out of all cases, 547 (77,6%) were localized in the parotid gland, 80 (11,3%) in submandibular gland and 78 (11,1%) in minor salivary glands. Nonmalignant tumors were more frequent in the parotid gland (82,8%) and submandibular gland (71,3%), whereas in minor salivary glands nonmalignant and malignant neoplasms the occurrence was nearly the same. In general-the smaller the salivary gland, the risk of development malignant tumors was higher. In group of nonmalignant salivary gland tumors two histopathological types dominated - pleomorphic adenoma and Warthin's tumor, which comprised 91,8% of the whole group. In the group of 153 malignant salivary gland tumors the most common histopathology were - adenoid cystic carcinoma, mucoepidermoid carcinoma and adenocarcinoma. In the analyzed period of 20 years' time, the incidence of salivary glands tumors increased with high siginificance, both for nonmalignant, as well malignant tumors.
国家癌症登记处记录的有关源自唾液腺的罕见肿瘤组的流行病学数据不足,因为它仅记录恶性唾液腺肿瘤。
699例唾液腺肿瘤患者(n = 705)的流行病学和临床特征。
数据取自凯尔采地区医院耳鼻喉科(1989年9月1日 - 2001年2月28日)以及凯尔采圣十字癌症中心头颈外科耳鼻喉科(2001年3月1日 - 2008年12月31日)。
在分析的699例患有705个唾液腺肿瘤的患者组中,女性占主导,占全组的54.2%。恶性肿瘤组的平均年龄高于非恶性肿瘤组。恶性肿瘤发生的风险随患者年龄增加而增加。在分析的705个唾液腺肿瘤组中,非恶性肿瘤占主导——78.3%。在所有病例中,547例(77.6%)位于腮腺,80例(11.3%)位于下颌下腺,78例(11.1%)位于小唾液腺。非恶性肿瘤在腮腺(82.8%)和下颌下腺(71.3%)中更常见,而在小唾液腺中,非恶性和恶性肿瘤的发生率几乎相同。总体而言——唾液腺越小,发生恶性肿瘤的风险越高。在非恶性唾液腺肿瘤组中,两种组织病理学类型占主导——多形性腺瘤和沃辛瘤,占整个组的91.8%。在153例恶性唾液腺肿瘤组中,最常见的组织病理学类型是——腺样囊性癌、黏液表皮样癌和腺癌。在分析的20年期间,唾液腺肿瘤的发病率均显著增加,无论是非恶性肿瘤还是恶性肿瘤。