Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
J Dent Res. 2013 Jul;92(7):592-7. doi: 10.1177/0022034513490168. Epub 2013 May 29.
The Global Burden of Disease (GBD) 2010 Study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990. We used disability-adjusted life-years (DALYs) and years lived with disability (YLDs) metrics to quantify burden. Oral conditions affected 3.9 billion people, and untreated caries in permanent teeth was the most prevalent condition evaluated for the entire GBD 2010 Study (global prevalence of 35% for all ages combined). Oral conditions combined accounted for 15 million DALYs globally (1.9% of all YLDs; 0.6% of all DALYs), implying an average health loss of 224 years per 100,000 population. DALYs due to oral conditions increased 20.8% between 1990 and 2010, mainly due to population growth and aging. While DALYs due to severe periodontitis and untreated caries increased, those due to severe tooth loss decreased. DALYs differed by age groups and regions, but not by genders. The findings highlight the challenge in responding to the diversity of urgent oral health needs worldwide, particularly in developing communities.
2010 年全球疾病负担研究对 1990 年、2005 年和 2010 年 291 种疾病和伤害造成的负担进行了可比估计。本文报告了 2010 年未经治疗的龋齿、严重牙周炎和严重牙齿缺失的全球负担，并将这些数据与 1990 年的新估计数进行了比较。我们使用残疾调整生命年（DALY）和伤残生存年（YLD）指标来量化负担。口腔疾病影响了 39 亿人，未经治疗的恒牙龋齿是整个 2010 年全球疾病负担研究评估的最普遍的疾病（所有年龄组的总患病率为 35%）。口腔疾病在全球造成了 1500 万残疾调整生命年（占所有 YLD 的 1.9%；占所有 DALY 的 0.6%），意味着每 10 万人平均损失 224 年健康寿命。1990 年至 2010 年期间，口腔疾病造成的残疾调整生命年增加了 20.8%，主要是由于人口增长和人口老龄化。虽然严重牙周炎和未经治疗的龋齿造成的 DALY 增加了，但严重牙齿缺失造成的 DALY 减少了。DALY 因年龄组和地区而异，但不因性别而异。这些发现强调了应对全球紧急口腔健康需求多样性的挑战，尤其是在发展中社区。
