宏观尺度下的人类连接组成像。

Center for the Developing Brain, Child Mind Institute, New York, New York, USA.

Nat Methods. 2013 Jun;10(6):524-39. doi: 10.1038/nmeth.2482.

At macroscopic scales, the human connectome comprises anatomically distinct brain areas, the structural pathways connecting them and their functional interactions. Annotation of phenotypic associations with variation in the connectome and cataloging of neurophenotypes promise to transform our understanding of the human brain. In this Review, we provide a survey of magnetic resonance imaging–based measurements of functional and structural connectivity. We highlight emerging areas of development and inquiry and emphasize the importance of integrating structural and functional perspectives on brain architecture.

在宏观尺度上，人类连接组由解剖上不同的大脑区域、连接它们的结构通路以及它们的功能相互作用组成。对连接组中表型关联的注释以及神经表型的编目有望改变我们对人类大脑的理解。在这篇综述中，我们提供了基于磁共振成像的功能和结构连接测量的概述。我们强调了新兴的发展和研究领域，并强调了整合大脑结构的结构和功能观点的重要性。