Sugiyama K, Ogino T, Ogata K
Department of Pharmacology, Okayama University Dental School, Japan.
Arch Oral Biol. 1990;35(6):415-9. doi: 10.1016/0003-9969(90)90202-l.
Three different polypeptides capable of stimulating histamine release from mast cells were isolated from human whole saliva, using heparin-gel chromatography followed by reversed-phase HPLC. The amino acid sequences of these peptides were shown to be identical to those of histatins 1, 3 and 5.
通过肝素凝胶色谱法继以反相高效液相色谱法，从人全唾液中分离出三种能够刺激肥大细胞释放组胺的不同多肽。这些肽的氨基酸序列显示与组胺素1、3和5的氨基酸序列相同。
