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从人全唾液中快速纯化和鉴定富组蛋白(富含组氨酸的多肽)

Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva.

作者信息

Sugiyama K, Ogino T, Ogata K

机构信息

Department of Pharmacology, Okayama University Dental School, Japan.

出版信息

Arch Oral Biol. 1990;35(6):415-9. doi: 10.1016/0003-9969(90)90202-l.

Abstract

Three different polypeptides capable of stimulating histamine release from mast cells were isolated from human whole saliva, using heparin-gel chromatography followed by reversed-phase HPLC. The amino acid sequences of these peptides were shown to be identical to those of histatins 1, 3 and 5.

摘要

通过肝素凝胶色谱法继以反相高效液相色谱法,从人全唾液中分离出三种能够刺激肥大细胞释放组胺的不同多肽。这些肽的氨基酸序列显示与组胺素1、3和5的氨基酸序列相同。

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