Kothari Dimple, Doshi Bhavana, Garg Gaurav, Khopkar Uday S
Department of Dermatology, Seth G.S. Medical College and K.E.M. Hospital, Mumbai, Maharashtra, India.
Indian J Dermatol. 2013 May;58(3):244. doi: 10.4103/0019-5154.110877.
We wish to report two cases of rickets due to vitamin D deficiency secondary to underlying ichthyotic skin disorder. The first case is of an 8-year-old male with history of multiple fluid-filled lesions over the body that would rupture to heal with thickening and scaling of skin, suggestive of epidermolytic hyperkeratosis, and the second is of a 14-year-old female with thick, large, quadrilateral scales over the extremities and back clinically consistent with lamellar ichthyosis. Both showed improvement with parenteral vitamin D3 and oral calcium supplements in addition to topical emollients.
我们希望报告两例因潜在鱼鳞病性皮肤病继发维生素D缺乏所致的佝偻病病例。第一例为一名8岁男性，有全身多处充满液体的皮损病史，皮损破溃后愈合，伴有皮肤增厚和脱屑，提示表皮松解性角化过度；第二例为一名14岁女性，四肢和背部有厚大的四边形鳞屑，临床符合板层状鱼鳞病。除局部使用润肤剂外，两例患者经肠外补充维生素D3和口服钙剂后均有改善。
