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正念冥想对医学生血清皮质醇的影响。

Effects of mindfulness meditation on serum cortisol of medical students.

作者信息

Turakitwanakan Wanpen, Mekseepralard Chantana, Busarakumtragul Panaree

机构信息

Department of Psychiatry, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand.

出版信息

J Med Assoc Thai. 2013 Jan;96 Suppl 1:S90-5.

PMID:23724462
Abstract

BACKGROUND

Mindfulness meditation is a method to relax the mind that decreases stress, which otherwise would increase serum cortisol. So, mindfulness meditation should decrease serum cortisol.

OBJECTIVE

To study the effect of mindfulness meditation on mental health by using Thai GHQ28 questionaire and study the effect of mindfulness meditation on stress by using serum cortisol.

MATERIAL AND METHOD

Volunteer subjects were 30 second year medical students, aged 19.1 +/- 0.55 year olds (range 18-20) from Srinakharinwirot University. They were screened by Thai GHQ28 and blood was drawn to measure cortisol at 8:00 am before and after a four-day mindfulness meditation programme. The comparison of Thai GHQ28 scores and serum cortisol levels before and after meditation were analysed by paired t-test.

RESULTS

The subjects were 66.77% female and 33.33% male. The average score of Thai GHQ28 before and after the mindfulness meditation was 1.50 (SD 2.53) and 0.77 (SD 2.08) respectively. The average serum cortisol levels before mindfulness meditation was 381.93 nmol/L (SD 97.74) becoming significantly lower after mindfulness meditation 306.38 nmol/L (SD 90.95). The difference was statistically significant in cortisol level, but not statistically significant in Thai GHQ28.

CONCLUSION

Mindfulness meditation lowers the cortisol levels in the blood suggesting that it can lower stress and may decrease the risk of diseases that arise from stress such as psychiatric disorder, peptic ulcer and migraine. Then, mindfulness meditation should be used in combination with standard treatment.

摘要

背景

正念冥想是一种放松心灵的方法,可减轻压力,否则压力会导致血清皮质醇升高。因此,正念冥想应能降低血清皮质醇水平。

目的

使用泰国一般健康问卷28项(Thai GHQ28)研究正念冥想对心理健康的影响,并通过血清皮质醇研究正念冥想对压力的影响。

材料与方法

志愿者为30名诗纳卡宁威洛大学的二年级医学生,年龄为19.1±0.55岁(范围18 - 20岁)。他们接受了泰国GHQ28筛查,并在为期四天的正念冥想课程前后的上午8点抽取血液以测量皮质醇。通过配对t检验分析冥想前后泰国GHQ28评分和血清皮质醇水平的比较。

结果

受试者中女性占66.77%,男性占33.33%。正念冥想前后泰国GHQ28的平均得分分别为1.50(标准差2.53)和0.77(标准差2.08)。正念冥想前血清皮质醇平均水平为381.93nmol/L(标准差97.74),正念冥想后显著降低至306.38nmol/L(标准差90.95)。皮质醇水平差异具有统计学意义,但泰国GHQ28差异无统计学意义。

结论

正念冥想可降低血液中的皮质醇水平,表明它能减轻压力,并可能降低由压力引起的疾病风险,如精神障碍、消化性溃疡和偏头痛。因此,正念冥想应与标准治疗联合使用。

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