Cazacu Irina Mihaela, Luzuriaga Chavez Adriana Alexandra, Saftoiu Adrian, Bhutani Manoop S
Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Gastroenterology, Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Craiova, Romania.
Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Endosc Ultrasound. 2019 Jan-Feb;8(1):17-24. doi: 10.4103/eus.eus_25_18.
There is an increasing global interest in screening programs aiming to detect pancreatic cancer (PC) in an early and potentially curable stage. Concerns still remain as to whether screening would confer any survival benefit. Another approach to evaluate the benefits of the pancreatic screening programs would be to consider its impact on the quality of life of the individuals who at risk of developing cancer. The aim of this systematic review was to investigate the current knowledge regarding the psychological impact of participation in routine screening for PC.
A systematic literature search was carried out in January 2018 in three major databases which are as follows: PubMed, Scopus, and Web of Science. Cross-sectional and prospective studies evaluating the psychological aspects of screening in high-risk individuals were included in the study. For each study, the following data were recorded: name of first author, year of publication, study design, study population, aims, screening protocol, outcomes and instruments, main results, and summary of findings.
Six cohort studies and one cross-sectional study that addressed the psychological aspects of PC screening were included in the analysis. Overall, studies have shown that high-risk individuals have positive psychological outcomes from participating in PC screening programs.
Although screening might not always be reassuring, it may improve individuals' quality of life, and this should be an important aspect when considering PC screening.
全球对于旨在在早期且可能治愈阶段检测出胰腺癌（PC）的筛查项目的兴趣日益浓厚。对于筛查是否能带来生存获益，人们仍存在担忧。评估胰腺癌筛查项目益处的另一种方法是考虑其对有患癌风险个体生活质量的影响。本系统评价的目的是调查关于参与胰腺癌常规筛查的心理影响的现有知识。
2018年1月在以下三个主要数据库中进行了系统的文献检索：PubMed、Scopus和Web of Science。纳入研究评估高危个体筛查心理方面的横断面研究和前瞻性研究。对于每项研究，记录以下数据：第一作者姓名、发表年份、研究设计、研究人群、目的、筛查方案、结果与工具、主要结果以及研究结果总结。
分析纳入了六项队列研究和一项涉及胰腺癌筛查心理方面的横断面研究。总体而言，研究表明高危个体参与胰腺癌筛查项目会有积极的心理结果。
尽管筛查可能并不总是令人安心，但它可能会改善个体的生活质量，而这在考虑胰腺癌筛查时应是一个重要方面。
