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分析 2010 年 10 月至 2011 年 12 月意大利全国麻疹监测数据,以及实现 2015 年消除麻疹目标的优先事项。

Analysis of national measles surveillance data in Italy from October 2010 to December 2011 and priorities for reaching the 2015 measles elimination goal.

机构信息

Infectious Diseases Epidemiology Unit, National Institute of Health, Rome, Italy.

出版信息

Euro Surveill. 2013 May 16;18(20):20480.

PMID:23725868
Abstract

From 1 October 2010 to 31 December 2011, Italy experienced high measles burden with 5,568 measles cases (37.4% laboratory-confirmed) reported to the enhanced measles surveillance system (cumulative incidence in the 15-month reference period: 9.2/100,000 population). Adolescents and young adults were especially affected, and the median age of cases was 18 years. Most cases (95.8%) were either unvaccinated or incompletely vaccinated. Complications were reported for 20.3% of cases, including 135 cases of pneumonia, seven of encephalitis and one case of Guillain–Barré syndrome. One death occurred in an immunocompromised adult. Over 1,300 cases were hospitalised. Identified priorities for reaching the measles elimination goal include evidence-based interventions such as reminder/recall for both doses of measles vaccine, supplementary immunisation activities aimed at susceptible age cohorts, and vaccinating healthcare workers.

摘要

从 2010 年 10 月 1 日至 2011 年 12 月 31 日,意大利麻疹负担较高,向强化麻疹监测系统报告了 5568 例麻疹病例(37.4%为实验室确诊)(15 个月参考期累计发病率:9.2/100000 人口)。青少年和年轻成年人受影响尤其严重,病例的中位数年龄为 18 岁。大多数病例(95.8%)未接种或未完全接种疫苗。报告了 20.3%的病例出现并发症,包括 135 例肺炎、7 例脑炎和 1 例格林-巴利综合征。一名免疫功能低下的成年人死亡。超过 1300 例住院。为实现消除麻疹目标,确定的优先事项包括基于证据的干预措施,如麻疹疫苗两剂次的提醒/召回、针对易感年龄组的补充免疫活动以及为卫生保健工作者接种疫苗。

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