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麻醉诱导时胃食管反流的发生与胃内容物量无关。

Occurrence of gastroesophageal reflux on induction of anaesthesia does not correlate with the volume of gastric contents.

作者信息

Hardy J F, Lepage Y, Bonneville-Chouinard N

机构信息

Department of Anaesthesia, University of Montreal, Quebec.

出版信息

Can J Anaesth. 1990 Jul;37(5):502-8. doi: 10.1007/BF03006316.

Abstract

In an attempt to explain the discrepancy between the high number of patients said to be at risk of aspiration pneumonitis and the low reported incidence of this anaesthetic complication, 100 ASA physical status I-II elective surgical patients were studied. The volume of fluid present in the stomach at the time of induction of anaesthesia was correlated with gastroesophageal reflux (GER) detected by visual inspection of the pharynx and by continuous measurement of upper oesophageal pH. Mean gastric volume was 30 +/- 28 ml (range 0-210 ml). Gastric fluid volume greater than or equal to 0.4 ml.kg-1 at pH less than or equal to 2.5 was present in 46 patients. No GER was detected during induction of anaesthesia in our sample of 100 patients. Furthermore, patient age, duration of preoperative fasting, body mass index, cigarette smoking, alcohol consumption, preoperative anxiety, and a history of preoperative GER were not correlated with significant modifications of gastric volume or pH. We conclude that the low incidence of aspiration pneumonitis in elective surgical patients may be explained in part by the very low risk of GER, despite gastric fluid volumes of more than 0.4 ml.kg-1 in a high proportion of this patient population.

摘要

为了解释据称有吸入性肺炎风险的患者数量众多与该麻醉并发症报告的低发生率之间的差异,对100例美国麻醉医师协会(ASA)身体状况I-II级的择期手术患者进行了研究。麻醉诱导时胃内的液体量与通过直视咽部和连续测量食管上段pH值检测到的胃食管反流(GER)相关。平均胃内容量为30±28 ml(范围0-210 ml)。46例患者的胃内液体量在pH值小于或等于2.5时大于或等于0.4 ml·kg-1。在我们的100例患者样本中,麻醉诱导期间未检测到GER。此外,患者年龄、术前禁食时间、体重指数、吸烟、饮酒、术前焦虑以及术前GER病史与胃内容量或pH值的显著变化无关。我们得出结论,择期手术患者吸入性肺炎的低发生率部分可能是由于GER风险极低,尽管该患者群体中很大一部分胃内液体量超过0.4 ml·kg-1。

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