Muuka Geoffrey Munkombwe, Chikampa Webster, Mundia Cornelius, Buonavoglia Domenico, Pini Atilio, Scacchia Massimo
Ministry of Agriculture and Livestock, Lusaka, Zambia,
Trop Anim Health Prod. 2014 Feb;46(2):481-3. doi: 10.1007/s11250-013-0429-9. Epub 2013 Jun 2.
Contagious bovine pleuropneumonia (CBPP), a highly infectious and fatal disease of cattle present in many countries in sub-Saharan Africa, is usually controlled by mass vaccinations. However, vaccination against CBPP is known to cause site reactions in a percentage of cattle especially in primary vaccinations. In Zambia, a record of site reactions was kept for seven consecutive years from 2005 to 2011 to establish the level of the problem. In some areas, after 3 years of consecutive vaccination campaigns, immunization could not be implemented for a period of 2 years because of logistical difficulties or owner resistance. Whereas in the three preceding years when animals were vaccinated annually, site reactions were in the range of 6.2%; on resumption of vaccination in the herds that had not been immunized for 2 years, site reactions averaged 21.3%. This data shows that the T1/44 vaccine may cause severe local reactions in cattle if there is any break in annual vaccinations. It is therefore important for authorities to ensure that the cattle at risk of contracting CBPP are regularly vaccinated to avoid discouraging farmers from presenting their animals.
牛传染性胸膜肺炎（CBPP）是撒哈拉以南非洲许多国家存在的一种牛的高度传染性致命疾病，通常通过大规模疫苗接种来控制。然而，已知针对CBPP的疫苗接种会在一定比例的牛身上引起局部反应，尤其是在初次接种时。在赞比亚，从2005年到2011年连续七年记录局部反应情况以确定问题的严重程度。在一些地区，经过连续三年的疫苗接种运动后，由于后勤困难或养殖户抵制，有两年时间无法进行免疫接种。在前三年每年给动物接种疫苗时，局部反应率在6.2%的范围内；在未免疫接种达两年的畜群恢复接种时，局部反应平均为21.3%。该数据表明，如果年度疫苗接种中断，T1/44疫苗可能会在牛身上引起严重的局部反应。因此，当局必须确保有感染CBPP风险的牛定期接种疫苗，以免打消养殖户送牛接种的积极性。
