Sylla D, Litamoi J, Rweyemamu M M
Pan African Veterinary Vaccine Centre, Addis Abeba, Ethiopie.
Rev Sci Tech. 1995 Sep;14(3):577-92.
Contagious bovine pleuropneumonia (CBPP) is regarded as the second most important disease of cattle in Africa. The disease was eradicated from Europe through drastic slaughter campaigns with quarantine and restriction of cattle movements. CBPP was mastered in Australia using these methods combined with vaccination. However, the disease remains endemic in Asia and Africa, where it inhibits livestock farming. In these continents, vaccination is the preferred means of control; the aim is to reduce incidence until complementary disease control measures can be applied. The success of a vaccination campaign depends on four main factors: good planning and good organisation; staff who are well-trained, fully equipped and highly motivated; high quality vaccines; good international co-operation. Vaccine strains recommended for use in Africa are strain T1/44 and its variant T1-SR. To improve the immunogenicity of these strains, the Pan African Rinderpest Campaign (PARC) secured financial support for research into immunostimulating complexes (ISCOM). It is hoped that this technology can improve vaccines, leading to effective eradication of the disease. In the meanwhile, systematic and repeated vaccination is the method of choice against CBPP in Africa.
牛传染性胸膜肺炎(CBPP)被视为非洲第二重要的牛病。欧洲通过大规模扑杀行动以及对牛只移动的检疫和限制,根除了这种疾病。澳大利亚采用这些方法并结合疫苗接种,控制住了CBPP。然而,该病在亚洲和非洲仍然流行,阻碍着畜牧业发展。在这些大陆,疫苗接种是首选的防控手段;目标是降低发病率,直到能够采取补充性疾病防控措施。疫苗接种行动的成功取决于四个主要因素:良好的规划和组织;训练有素、装备齐全且积极性高的工作人员;高质量疫苗;良好的国际合作。推荐在非洲使用的疫苗株是T1/44株及其变体T1-SR。为提高这些毒株的免疫原性,泛非牛瘟运动(PARC)获得了资金支持,用于免疫刺激复合物(ISCOM)的研究。希望这项技术能够改进疫苗,从而有效根除该病。与此同时,在非洲,系统且反复的疫苗接种是防控CBPP的首选方法。