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伊拉克白塞病遗传学的比较研究:开展国际合作,向巴格达医学院及医院传授临床和实验室技能。

A comparative study of the genetics of Behcet's disease in Iraq: international collaboration to transfer clinical and laboratory skills to Baghdad medical school and hospitals.

作者信息

Tappuni A R, Tbakhi A, Sharquie K E, Hayani R K, Al-Kaisi A, Lafi A, Al-Araji A

机构信息

Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

出版信息

Med Confl Surviv. 2013 Jan-Mar;29(1):57-68. doi: 10.1080/13623699.2013.765201.

Abstract

A collaborative project funded by the Iraqi Research Fellowship Programme of the Council for Assisting Refugee Academics was set up to transfer laboratory and clinical skills in between three clinical research teams in the UK, Jordan and Iraq. The project was set up to study the genetics of the potentially debilitating condition, Behçet's Disease (BD). Blood samples were collected from: 38 BD patients, 28 patients with oral ulcers not related to BD and 32 healthy controls. All samples were analysed using Micro SSP HLA Class I B locus kit (B locus, generic). Logistic regression analysis revealed that samples positive for HLA-B51 were 7.4 times more likely to have BD than the healthy control subjects. The results of this study make a valuable addition to the scientific literature. Additional valuable outcomes include the intellectual exchange and transfer of skills in between the collaborating teams, which led to the establishment of an international research collaboration.

摘要

由援助难民学者理事会伊拉克研究奖学金计划资助的一个合作项目得以设立,目的是在英国、约旦和伊拉克的三个临床研究团队之间传授实验室和临床技能。该项目旨在研究可能使人衰弱的白塞病(BD)的遗传学。血液样本采集自:38名BD患者、28名与BD无关的口腔溃疡患者和32名健康对照者。所有样本均使用微量序列特异性引物HLA I类B位点试剂盒(B位点,通用型)进行分析。逻辑回归分析显示,HLA - B51呈阳性的样本患BD的可能性是健康对照者的7.4倍。这项研究的结果为科学文献增添了有价值的内容。其他有价值的成果包括合作团队之间的知识交流和技能传授,这促成了一项国际研究合作的建立。

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