Suppr超能文献

Thymus lymphocytes in uraemic rats and the effect of thymosin fraction 5 in vitro.

作者信息

Ikemoto S, Kishimoto T, Wada S, Hayahara N, Maekawa M

机构信息

Department of Urology, Osaka City University Medical School, Japan.

出版信息

Clin Exp Immunol. 1990 Jun;80(3):474-7. doi: 10.1111/j.1365-2249.1990.tb03312.x.

DOI:10.1111/j.1365-2249.1990.tb03312.x
PMID:2372994
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1535211/
Abstract

Cellular immunity of thymus lymphocytes in uraemic rats was studied. Severe and moderate uraemia was induced in rats, and sham-operated and normal rats were used as the controls. As a result, the response of thymus lymphocytes to concanavalin A (Con A) significantly decreased in severely uraemic rats, but did not change in moderately uraemic rats. However, when the thymus lymphocytes were pretreated with thymosin fraction 5, the response to Con A was ameliorated in severely uraemic rats. There was a significant correlation between the effect of thymosin fraction 5 on Con A response and Con A response of thymus lymphocytes. In addition, serum from severe uraemic rats suppressed the response of normal thymus lymphocytes to Con A. These results indicate that severe uraemia may cause an impairment in maturation of thymus lymphocytes, which can be improved by thymosin fraction 5 in vitro.

摘要

相似文献

1
Thymus lymphocytes in uraemic rats and the effect of thymosin fraction 5 in vitro.
Clin Exp Immunol. 1990 Jun;80(3):474-7. doi: 10.1111/j.1365-2249.1990.tb03312.x.
2
Thymus lymphocytes in uraemic rats and the effect of thymosin fraction 5 in vivo.尿毒症大鼠的胸腺淋巴细胞及胸腺素5组分的体内作用
Clin Exp Immunol. 1992 Feb;87(2):220-3. doi: 10.1111/j.1365-2249.1992.tb02978.x.
3
Host immune status in uraemia. II. Serum factors and lymphocyte transformation.尿毒症患者的宿主免疫状态。II. 血清因子与淋巴细胞转化
Clin Exp Immunol. 1980 Jul;41(1):123-9.
4
Thymus lymphocytes in rats during induction of bladder tumors and effects of thymosin fraction 5 in vitro.大鼠膀胱肿瘤诱导过程中的胸腺淋巴细胞及胸腺素5组分的体外作用
J Natl Cancer Inst. 1985 Mar;74(3):659-64.
5
Thymic functions in uremic rats: evidence for thymosin alpha 1 deficiency.尿毒症大鼠的胸腺功能：胸腺素α1缺乏的证据。
Nephron. 1985;39(4):365-70. doi: 10.1159/000183407.
6
The role of the maturation stage of thymocytes on the phytohemagglutinin and concanavalin A responses in thymocyte and lymph node lymphocyte cocultures in guinea pig. Effects of pretreatment of thymocytes with thymosin or levamisole.豚鼠胸腺细胞与淋巴结淋巴细胞共培养体系中，胸腺细胞成熟阶段对其植物血凝素和刀豆球蛋白A反应的作用。胸腺素或左旋咪唑预处理胸腺细胞的影响。
Immunopharmacology. 1981 Feb;3(1):83-91. doi: 10.1016/0162-3109(81)90042-4.
7
Host immune status in uraemia. I. Cell-mediated immune mechanisms.尿毒症患者的宿主免疫状态。I. 细胞介导的免疫机制。
Clin Exp Immunol. 1980 Jul;41(1):115-22.
8
[Modulation of suppressor activity by thymosin].
C R Seances Soc Biol Fil. 1981;175(2):235-41.
9
Thymosin modulation of suppressor function in mice and man.
Ann N Y Acad Sci. 1979;332:95-100. doi: 10.1111/j.1749-6632.1979.tb47101.x.
10
The effect of thymosin on human T-cells from cancer patients.
Cancer. 1976 Jan;37(1):98-103. doi: 10.1002/1097-0142(197601)37:1<98::aid-cncr2820370114>3.0.co;2-3.

引用本文的文献

1
Thymus lymphocytes in uraemic rats and the effect of thymosin fraction 5 in vivo.尿毒症大鼠的胸腺淋巴细胞及胸腺素5组分的体内作用
Clin Exp Immunol. 1992 Feb;87(2):220-3. doi: 10.1111/j.1365-2249.1992.tb02978.x.

本文引用的文献

1
Experimental uremia. Description of a model producing varying degrees of stable uremia.实验性尿毒症。一种产生不同程度稳定尿毒症的模型的描述。
Nephron. 1980;26(5):249-54. doi: 10.1159/000181994.
2
Immune response in experimentally induced uremia. I. Suppression of mitogen responses by adherent cells in chronic uremia.实验性诱导尿毒症中的免疫反应。I. 慢性尿毒症中黏附细胞对有丝分裂原反应的抑制
Clin Immunol Immunopathol. 1981 Apr;19(1):8-18. doi: 10.1016/0090-1229(81)90043-x.
3
High incidence of neoplasia in uremic patients receiving long-term dialysis. Cancer and long-term dialysis.接受长期透析的尿毒症患者肿瘤发生率高。癌症与长期透析。
Nephron. 1981;27(6):292-6. doi: 10.1159/000182073.
4
Host immune status in uraemia. I. Cell-mediated immune mechanisms.尿毒症患者的宿主免疫状态。I. 细胞介导的免疫机制。
Clin Exp Immunol. 1980 Jul;41(1):115-22.
5
Humoral inhibitors of the immune response in uremia. V. Induction of suppressor cells in vitro by uremic serum.尿毒症中免疫反应的体液抑制剂。V. 尿毒症血清在体外诱导抑制细胞
Am J Pathol. 1983 May;111(2):149-55.
6
The effect of uremic plasma on lymphocyte transformation.尿毒症血浆对淋巴细胞转化的影响。
Invest Urol. 1967 Sep;5(2):195-9.
7
Defective cellular immunity in renal failure: depression of reactivity of lymphocytes to phytohemagglutinin by renal failure serum.肾衰竭中的细胞免疫缺陷：肾衰竭血清对淋巴细胞对植物血凝素反应性的抑制。
J Clin Invest. 1971 Jun;50(6):1262-71. doi: 10.1172/JCI106604.
8
Renal failure and infection.肾衰竭与感染。
Medicine (Baltimore). 1968 Jan;47(1):1-32. doi: 10.1097/00005792-196801000-00001.
9
Macromolecular inhibitor of lymphocyte transformation in serum from patients with chronic renal failure.慢性肾衰竭患者血清中淋巴细胞转化的大分子抑制剂。
Aust J Exp Biol Med Sci. 1973 Apr;51(2):259-62. doi: 10.1038/icb.1973.24.
10
Purification and biological activity of thymosin, a hormone of the thymus gland.胸腺素（一种胸腺分泌的激素）的纯化及生物活性
Proc Natl Acad Sci U S A. 1972 Jul;69(7):1800-3. doi: 10.1073/pnas.69.7.1800.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验