Srivastava Reena, Sharma Neela Rai, Kushwaha K P, Aditya Vani
Department of Obstetrics and Gynecology, B.R.D. Medical College, Gorakhpur, India.
J Obstet Gynaecol India. 2012 Jun;62(3):276-80. doi: 10.1007/s13224-012-0215-z. Epub 2012 Aug 1.
To perform analyses of maternal and fetal complications in overweight and obese women.
Eighty-seven women with singleton pregnancies with BMI > 25-29.9 kg/m(2) and 83 women with singleton pregnancies with BMI > 30 kg/m(2) were studied for maternal and fetal complications at Nehru Hospital, B.R.D. Medical College, Gorakhpur during June 2007-October 2008. Forty-five women with BMI 20-24.9 kg/m(2) were selected to serve as control.
Compared with women with normal BMI, the outcomes which were more common in overweight and obese women were gestation hypertension (p < 0.05); pre-eclampsia (p < 0.001); preterm delivery (p < 0.05); induction of labor (p < 0.05); instrumental vaginal delivery (p > 0.05); cesarean section (p < 0.01); increased operative time (p < 0.01); still births (p < 0.05); early neonatal deaths (p < 0.05); Apgar score < 7 at 5 min (p < 0.05); and admission to NICU (p < 0.001). No significant differences were noted among groups regarding hypoglycemia hyperbilirubinemia and respiratory distress.
Overweight and obesity are definite risk factors for adverse pregnancy outcomes. This may be due to altered metabolic state in obesity.
分析超重和肥胖女性的母婴并发症。
2007年6月至2008年10月期间,在戈勒克布尔市B.R.D.医学院尼赫鲁医院,对87名单胎妊娠且BMI>25-29.9kg/m²的女性以及83名单胎妊娠且BMI>30kg/m²的女性进行母婴并发症研究。选取45名BMI为20-24.9kg/m²的女性作为对照。
与BMI正常的女性相比,超重和肥胖女性中更常见的结局包括妊娠期高血压(p<0.05);子痫前期(p<0.001);早产(p<0.05);引产(p<0.05);器械助产阴道分娩(p>0.05);剖宫产(p<0.01);手术时间延长(p<0.01);死产(p<0.05);早期新生儿死亡(p<0.05);5分钟时阿氏评分<7(p<0.05);以及入住新生儿重症监护病房(p<0.001)。各组在低血糖、高胆红素血症和呼吸窘迫方面未观察到显著差异。
超重和肥胖是不良妊娠结局的明确危险因素。这可能是由于肥胖时代谢状态改变所致。