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骶髂关节的微创融合术:既往腰椎融合术会影响患者的预后吗?

MIS Fusion of the SI Joint: Does Prior Lumbar Spinal Fusion Affect Patient Outcomes?

作者信息

Rudolf Leonard

机构信息

129 Mascoma Street, Lebanon, NH 03766, USA.

出版信息

Open Orthop J. 2013 May 17;7:163-8. doi: 10.2174/1874325001307010163. Print 2013.

Abstract

BACKGROUND

Sacroiliac (SI) joint pain is a challenging condition to manage as it can mimic discogenic or radicular low back pain, and present as low back, hip, groin and/or buttock pain. Patients may present with a combination of lumbar spine and SI joint symptoms, further complicating the diagnosis and treatment algorithm [1-3]. SI joint pain after lumbar spinal fusion has been reported in the literature. Both clinical and biomechanical studies show the SI joint to be susceptible to increased motion and stress at the articular surface with up to 40-75% of patients developing significant SI joint degeneration after 5 years. In a recent case series study of 50 patients who underwent minimally invasive SI joint arthrodesis, 50% had undergone previous lumbar spinal fusion and 18% had symptomatic lumbar spine pathology treated conservatively [4]. The purpose of this study is to determine if history of previous lumbar fusion or lumbar pathology affects patient outcomes after MIS SI joint fusion surgery.

METHODS

We report on 40 patients with 24 month follow up treated with MIS SI joint fusion using a series of triangular porous plasma coated titanium implants (iFuse, SI-Bone, Inc. San Jose, CA). Outcomes using a numerical rating scale (NRS) for pain were obtained at 3-, 6-, 12- and 24 month follow up intervals. Additionally, patient satisfaction was collected at the latest follow up interval. Patients were separated into 3 cohorts: 1) underwent prior lumbar spine fusion (PF), 2) no history of previous lumbar spine fusion (NF), 3) no history of previous lumbar spine fusion with symptomatic lumbar spine pathology treated conservatively (LP). A repeated measures analysis of variance (rANOVA) was used to determine if the change in NRS pain scores differed across timepoints and subgroups. A decrease in NRS by 2 points was deemed clinically significant [5].

RESULTS

Mean age was 54 (±13) years and varied slightly but not statistically between groups. All subgroups experienced a clinically and statistically significant reduction in pain at all time points (mean change >2 points, p<0.001). There was a statistically significant effect of cohort (p=0.045), with the NF cohort (no prior lumbar spinal fusion) having a somewhat greater decrease in pain (by approximately 1 point) compared to the other 2 groups (PF and LP).Patient reported satisfaction by cohort was: 89% (NF), 92% (PF) and 63% (LP).Overall satisfaction rate was 87%.

DISCUSSION AND CONCLUSION

Patients with SI joint pain, regardless of prior lumbar spine fusion history, show significant improvement in pain after minimally invasive SI joint fusion. The presence of symptomatic lumbar spine pathology potentially confounds the treatment affect, as patients may not be able to discriminate between symptoms arising from the SI joint and the lumbar spine. These patients expressed a lower satisfaction with surgery. Patients without other confounding lumbar spine pathology and who have not undergone previous spine surgery tend to be younger and experience a greater reduction in pain.

摘要

背景

骶髂(SI)关节疼痛是一种难以处理的病症,因为它可能类似于椎间盘源性或神经根性下腰痛,并表现为下背部、臀部、腹股沟和/或臀部疼痛。患者可能同时出现腰椎和骶髂关节症状,这进一步使诊断和治疗方案变得复杂[1-3]。文献中已报道了腰椎融合术后的骶髂关节疼痛。临床和生物力学研究均表明,骶髂关节在关节表面易出现活动增加和应力增大的情况,高达40-75%的患者在5年后会出现明显的骶髂关节退变。在最近一项对50例行微创骶髂关节融合术患者的病例系列研究中,50%的患者曾接受过腰椎融合术,18%的患者有经保守治疗的有症状腰椎病变[4]。本研究的目的是确定既往腰椎融合史或腰椎病变是否会影响微创骶髂关节融合术后的患者预后。

方法

我们报告了40例接受微创骶髂关节融合术并随访24个月的患者,使用了一系列三角形多孔等离子涂层钛植入物(iFuse,SI-Bone公司,加利福尼亚州圣何塞)。在3个月、6个月、12个月和24个月的随访间隔时,采用数字评分量表(NRS)评估疼痛结果。此外,在最近的随访间隔时收集患者满意度。患者被分为3组:1)曾接受过腰椎融合术(PF),2)无既往腰椎融合史(NF),3)无既往腰椎融合史但有经保守治疗的有症状腰椎病变(LP)。采用重复测量方差分析(rANOVA)来确定NRS疼痛评分在各时间点和亚组之间的变化是否存在差异。NRS评分降低2分被认为具有临床意义[5]。

结果

平均年龄为54(±13)岁,各组之间略有差异但无统计学意义。所有亚组在所有时间点的疼痛均有临床和统计学意义的减轻(平均变化>2分,p<0.001)。组间存在统计学意义(p=0.045),与其他两组(PF和LP)相比,NF组(无既往腰椎融合史)的疼痛减轻幅度略大(约1分)。各队列患者报告的满意度为:89%(NF),92%(PF)和63%(LP)。总体满意度为87%。

讨论与结论

骶髂关节疼痛患者,无论既往有无腰椎融合史,在微创骶髂关节融合术后疼痛均有显著改善。有症状的腰椎病变可能会混淆治疗效果,因为患者可能无法区分骶髂关节和腰椎产生的症状。这些患者对手术的满意度较低。没有其他混杂腰椎病变且未接受过脊柱手术的患者往往更年轻,疼痛减轻幅度更大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e7/3664440/4827a3b44094/TOORTHJ-7-163_F1a.jpg

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