Department of Orthopaedic Surgery, Korea University Ansan Hospital, Ansan, Korea.
Clin Orthop Surg. 2013 Jun;5(2):110-7. doi: 10.4055/cios.2013.5.2.110. Epub 2013 May 15.
There has been controversy whether methylmethacrylate precoating of the cemented femoral stem is a solution for aseptic loosening or rather contributes to increased failure rates in cemented total hip arthroplasties.
On a retrospective basis, we analyzed 76 primary hybrid total hip arthroplasties from 63 patients with precoated, cemented femoral stems between October 1990 and December 1995. The mean age of the patients was 46.8 years (range, 22 to 77 years) with a minimum follow-up of 14 years (mean, 15.5 years; range, 14 to 19.5 years). Third generation cementing techniques were employed in all cases.
Twenty-four out of 76 cases (31.6%) showed aseptic loosening of the femoral stems, of which 23 stems were revised at an average revision time of 8 years (range, 3 to 14.8 years). The main mode of loosening was cement-stem interface failure in 22 hips (91.7%). Twenty-one out of 24 failed hips (87.5%) demonstrated C2 cementing grades (p < 0.001). Kaplan-Meier survivorship analysis using radiographic aseptic loosening of the femoral stem as the endpoint for failure showed survival rates of 76.5% at 10 years (95% confidence interval [CI], 71.4 to 81.6) and 63.2% at 19 years (95% CI, 57.3 to 69.1).
An early failure of the precoated femoral stem in this study was mainly due to an insufficient cementing technique. Achievement of good cement mantle may improve the survival rates.
关于甲基丙烯酸甲酯预涂骨水泥股骨柄是否是解决无菌性松动的方法,或者是否会增加骨水泥全髋关节置换术后失败率,一直存在争议。
我们回顾性分析了 1990 年 10 月至 1995 年 12 月期间 63 例使用预涂骨水泥股骨柄的初次混合全髋关节置换术 76 例患者的资料。患者的平均年龄为 46.8 岁(22 岁至 77 岁),随访时间至少 14 年(平均 15.5 年;范围 14 年至 19.5 年)。所有病例均采用第三代骨水泥技术。
76 例中有 24 例(31.6%)出现股骨柄无菌性松动,其中 23 例在平均 8 年(3 年至 14.8 年)时进行了翻修。主要松动模式为 22 髋(91.7%)的骨水泥-柄界面失败。24 例失败的髋关节中,有 21 例(87.5%)显示 C2 级骨水泥固定(p < 0.001)。以影像学股骨柄无菌性松动为失效终点的 Kaplan-Meier 生存分析显示,10 年时的生存率为 76.5%(95%置信区间[CI]:71.4%至 81.6%),19 年时为 63.2%(95%CI:57.3%至 69.1%)。
本研究中预涂股骨柄早期失效主要是由于骨水泥固定技术不足所致。良好的骨水泥覆盖层可能会提高生存率。