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环丙沙星引起的大疱性固定性药疹:一例报告

Bullous fixed drug eruption to ciprofloxacin: a case report.

作者信息

Jain Sonia Pramod, Jain Pramod Ajit

机构信息

Professor, Department of Skin and V.D., Mahatma Gandhi Institute of Medical Sciences , Sewagram, Wardha-442102, India .

出版信息

J Clin Diagn Res. 2013 Apr;7(4):744-5. doi: 10.7860/JCDR/2013/4757.2901. Epub 2013 Apr 1.

DOI:10.7860/JCDR/2013/4757.2901
PMID:23730666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3644464/
Abstract

Adverse reactions to medications are extremely common and display a characteristic clinical morphology such as fixed drug eruption (FDE), Stevens-Johnson syndrome, urticaria, morbilliform exanthem, hypersensitivity syndrome, pigmentary changes, lichenoid, dermatitis, acute generalized exanthematous pustulosis, photosensitivity, vasculitis etc. Here we report a case of a 60 year old male who presented to us with multiple bullous eruptions over both the hands and feet after oral ingestion of ciprofloxacin.

摘要

药物不良反应极为常见,并呈现出特征性的临床形态,如固定性药疹(FDE)、史蒂文斯 - 约翰逊综合征、荨麻疹、麻疹样皮疹、超敏反应综合征、色素沉着改变、苔藓样皮炎、急性泛发性脓疱性皮病、光敏反应、血管炎等。在此,我们报告一例60岁男性患者,其在口服环丙沙星后双手和双足出现多处大疱性皮疹。

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本文引用的文献

1
Ciprofloxacin-induced bullous fixed drug eruption.环丙沙星诱发的大疱性固定性药疹。
Indian J Dermatol Venereol Leprol. 1995 Jul-Aug;61(4):238-9.
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Fluoroquinolone-induced generalized fixed drug eruption.氟喹诺酮类药物引起的全身性固定性药疹。
Dermatol Online J. 2009 Dec 15;15(12):8.
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Psoriasiform fixed drug eruption caused by nimesulide.尼美舒利引起的银屑病样固定性药疹。
Clin Exp Dermatol. 2009 Oct;34(7):e360-1. doi: 10.1111/j.1365-2230.2009.03315.x. Epub 2009 May 26.
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Oral fixed drug eruption caused by gabapentin.加巴喷丁引起的口腔固定性药疹。
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Ciprofloxacin-induced generalized bullous fixed drug eruption.
Indian J Dermatol Venereol Leprol. 2008 Sep-Oct;74(5):511-2. doi: 10.4103/0378-6323.44324.
6
Drug-related problems in hospitals: a review of the recent literature.医院中的药物相关问题:近期文献综述
Drug Saf. 2007;30(5):379-407. doi: 10.2165/00002018-200730050-00003.
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Vulvar fixed drug eruption. A report of 13 cases.
J Reprod Med. 2007 Feb;52(2):81-6.
8
Specific site involvement in fixed drug eruption.固定性药疹的特定部位受累情况。
J Am Acad Dermatol. 2003 Dec;49(6):1003-7. doi: 10.1016/s0190-9622(03)01588-3.
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Quinolone hypersensitivity.喹诺酮超敏反应。
Curr Opin Allergy Clin Immunol. 2003 Aug;3(4):275-81. doi: 10.1097/00130832-200308000-00007.
10
Fixed drug eruptions. Incidence, recognition, and avoidance.固定性药疹。发病率、识别与避免
Am J Clin Dermatol. 2000 Sep-Oct;1(5):277-85. doi: 10.2165/00128071-200001050-00003.