Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD 20892-7936, USA.
J Clin Hypertens (Greenwich). 2013 Jun;15(6):367-74. doi: 10.1111/jch.12088. Epub 2013 Apr 1.
Hypertension treatment regimens used by African American adults in the Jackson Heart Study were evaluated at the first two clinical examinations (2415 treated hypertensive persons at examination I [exam I], 2000-2004; 2577 at examination II [exam II], 2005-2008). Blood pressure (BP) was below 140/90 mm Hg for 66% and 70% of treated participants at exam I and exam II, respectively. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure treatment targets were met for 56% and 61% at exam I and exam II, respectively. Persons with diabetes or chronic kidney disease were less likely to have BP at target, as were men compared with women. Thiazide diuretics were the most commonly used antihypertensive medication, and persons taking a thiazide were more likely to have their BP controlled than persons not taking them; thiazides were used significantly less among men than women. Although calcium channel blockers are often considered to be effective monotherapy for African Americans, persons using calcium channel blocker monotherapy were significantly less likely to be at target BP than persons using thiazide monotherapy.
在杰克逊心脏研究中，研究人员评估了非裔美国成年人的高血压治疗方案，这些方案是在最初的两次临床检查中（第一次检查时，2415 名接受治疗的高血压患者[检查 I]，2000-2004 年；第二次检查时，2577 名患者[检查 II]，2005-2008 年）使用的。在检查 I 和检查 II 时，分别有 66%和 70%的治疗参与者的血压（BP）低于 140/90mmHg。第七次联合国家预防、检测、评估和治疗高血压报告的治疗目标分别在检查 I 和检查 II 时达到了 56%和 61%。患有糖尿病或慢性肾病的人血压达标率较低，男性与女性相比也是如此。噻嗪类利尿剂是最常用的降压药物，服用噻嗪类药物的人血压控制的可能性比不服用的人更大；噻嗪类药物在男性中的使用明显低于女性。虽然钙通道阻滞剂通常被认为是治疗非裔美国人的有效单药治疗药物，但使用钙通道阻滞剂单药治疗的人血压达标率明显低于使用噻嗪类单药治疗的人。
