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发育中大鼠脑和肝脏中铜、锌和锰超氧化物歧化酶活性的差异变化。

Differential changes in Cu, Zn and Mn superoxide dismutase activity in developing rat brain and liver.

作者信息

Mariucci G, Ambrosini M V, Colarieti L, Bruschelli G

机构信息

Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Italy.

出版信息

Experientia. 1990 Jul 15;46(7):753-5. doi: 10.1007/BF01939957.

DOI:10.1007/BF01939957
PMID:2373203
Abstract

The aim of our study was to assess the pattern of copper and zinc-containing superoxide dismutase (Cu, ZnSOD) and manganese-containing superoxide dismutase (MnSOD) activity from embryonic life to senescence in rat brain and liver. The two isoenzymes showed different profiles in the two organs examined. In particular, the cerebral MnSOD activity profile suggests a primary role during differentiation of this enzymatic form.

摘要

我们研究的目的是评估大鼠从胚胎期到衰老期大脑和肝脏中含铜锌超氧化物歧化酶（Cu，ZnSOD）和含锰超氧化物歧化酶（MnSOD）的活性模式。这两种同工酶在检测的两个器官中呈现出不同的分布。特别是，大脑中MnSOD的活性分布表明这种酶形式在分化过程中起主要作用。

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