Overesch G, Stephan R, Perreten V
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern.
Schweiz Arch Tierheilkd. 2013 Jun;155(6):339-50. doi: 10.1024/0036-7281/a000469.
We evaluated the susceptibility of the gram-positive mastitis pathogens S. aureus, Str. uberis, Str. dysgalactiae, E. faecalis and L. garviae to antibiotics that are of epidemiological interest or are critically important for mastitis therapy and human medicine. Penicillin resistance was found to be most frequent in S. aureus, and nearly 5 % of the Str. uberis strains displayed a decreased susceptibility to this antibiotic. Resistance to aminoglycosides and macrolides was also detected in the strains tested. The detection of methicillin-resistant S. aureus (MRSA) and of a ciprofloxacin-resistant Str. dysgalactiae isolate corroborated the emergence of mastitis pathogens resistant to critically important antibiotics and underscores the importance of susceptibility testing prior to antibiotic therapy. The monitoring of antibiotic susceptibility patterns and antibiogram analyses are strongly recommended for targeted antimicrobial treatment and to avoid the unnecessary use of the latest generation of antibiotics.
我们评估了革兰氏阳性乳腺炎病原体金黄色葡萄球菌、乳房链球菌、停乳链球菌、粪肠球菌和加氏乳杆菌对具有流行病学意义或对乳腺炎治疗及人类医学至关重要的抗生素的敏感性。发现青霉素耐药性在金黄色葡萄球菌中最为常见，近5%的乳房链球菌菌株对这种抗生素的敏感性降低。在所测试的菌株中还检测到对氨基糖苷类和大环内酯类抗生素的耐药性。耐甲氧西林金黄色葡萄球菌（MRSA）和一株耐环丙沙星的停乳链球菌分离株的检测证实了乳腺炎病原体对至关重要的抗生素产生耐药性的出现，并强调了在抗生素治疗前进行药敏试验的重要性。强烈建议监测抗生素敏感性模式并进行抗菌谱分析，以进行有针对性的抗菌治疗，并避免不必要地使用最新一代抗生素。
