定量性汗传交感反射测试的重测信度。

Test-retest reliability of quantitative sudomotor axon reflex testing.

机构信息

Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada.

出版信息

J Clin Neurophysiol. 2013 Jun;30(3):308-12. doi: 10.1097/WNP.0b013e3182873254.

DOI:10.1097/WNP.0b013e3182873254

PMID:23733097

Abstract

PURPOSE

To determine the reliability of quantitative sudomotor axon reflex testing (QSART).

METHODS

The QSART at four sites was performed at two time points (n = 20 healthy participants) to determine the intraclass correlation coefficient with 95% confidence intervals. The standard error of measurement and minimal detectable change for men and women was obtained from QSART values from a larger cohort (n = 67).

RESULTS

Intraclass correlation coefficients (95% confidence intervals) for the forearm, proximal leg, distal leg and foot were 0.75 (0.46 to 0.89), 0.49 (0.07 to 0.77), 0.71 (0.38 to 0.88) and 0.48 (0.07 to 0.76). Standard error of measurements ranged from 0.666 to 0.978 µL for men and 0.273 to 0.653 µL for women. Minimal detectable changes ranged from ±1.847 to ±2.712 µL for men and ±0.756 to ±1.809 µL for women.

CONCLUSIONS

We observed moderate test-retest reliability for QSART with a large standard error of measurements and minimal detectable changes for both men and women. The results of this study suggest limited utility of QSART for monitoring sudomotor function in longitudinal and interventional studies.

摘要

目的

确定定量性汗反射神经轴突测试（QSART）的可靠性。

方法

在两个时间点对 20 名健康参与者的四个部位进行 QSART，以确定 95%置信区间的组内相关系数。从更大队列（n = 67）的 QSART 值中获得男性和女性的测量标准误差和最小可检测变化。

结果

前臂、近端腿、远端腿和足部的组内相关系数（95%置信区间）分别为 0.75（0.46 至 0.89）、0.49（0.07 至 0.77）、0.71（0.38 至 0.88）和 0.48（0.07 至 0.76）。男性的测量标准误差范围为 0.666 至 0.978 µL，女性为 0.273 至 0.653 µL。男性的最小可检测变化范围为±1.847 至±2.712 µL，女性为±0.756 至±1.809 µL。