一种高灵敏度的共振瑞利散射方法，用于区分平行股 G-四链体与其他拓扑结构和结构的 DNA。
A highly sensitive resonance Rayleigh scattering method to discriminate a parallel-stranded G-quadruplex from DNA with other topologies and structures.
机构信息
Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Chemistry and Chemical Engineering, Southwest University, Chongqing, PR China.
出版信息
Chem Commun (Camb). 2013 Jul 14;49(55):6209-11. doi: 10.1039/c3cc42140f.
PMID:23736799
Abstract
The RRS intensities are significantly increased only when a parallel-stranded G-quadruplex is added to Mg(2+) solution owing to the formation of G-wires between them, but the others cannot. So, we constructed a new and highly sensitive RRS method to discriminate a parallel-stranded G-quadruplex from DNA with other topologies and structures.
摘要
只有当平行股的 G-四链体被添加到 Mg(2+)溶液中时，RRS 强度才会显著增加，这是由于它们之间形成了 G-线，而其他的则不能。因此，我们构建了一种新的、高灵敏度的 RRS 方法，以区分平行股的 G-四链体与具有其他拓扑结构和结构的 DNA。
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