Luque Antoni, Reguera David
Department of Fundamental Physics, Universitat de Barcelona, c/Martí i Franquès 1, 08028, Barcelona, Spain.
Subcell Biochem. 2013;68:553-95. doi: 10.1007/978-94-007-6552-8_19.
All matter has to obey the general laws of physics and living matter is not an exception. Viruses have not only learnt how to cope with them, but have managed to use them for their own survival. In this chapter we will review some of the exciting physics behind viruses and discuss simple physical models that can shed some light on different aspects of the viral life cycle and viral properties. In particular, we will focus on how the structure and shape of the capsid, its assembly and stability, and the entry and exit of viral particles and their genomes can be understood using fundamental physics theories.
所有物质都必须遵循物理学的一般规律,生物物质也不例外。病毒不仅学会了如何应对这些规律,还设法利用它们来实现自身的生存。在本章中,我们将回顾病毒背后一些令人兴奋的物理学知识,并讨论一些简单的物理模型,这些模型可以揭示病毒生命周期和病毒特性的不同方面。特别是,我们将重点探讨如何利用基础物理学理论来理解衣壳的结构和形状、其组装和稳定性,以及病毒颗粒及其基因组的进出。