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三级教学医院分娩时产妇椎管内镇痛的质量和满意度:一项前瞻性观察研究。

Quality of labour neuraxial analgesia and maternal satisfaction at a tertiary care teaching hospital: a prospective observational study.

机构信息

Department of Anesthesia and Pain Management, Mount Sinai Hospital, University of Toronto, 600 University Avenue, Room 781, Toronto, ON, M5G 1X5, Canada.

出版信息

Can J Anaesth. 2013 Aug;60(8):787-95. doi: 10.1007/s12630-013-9976-9. Epub 2013 Jun 5.

Abstract

PURPOSE

Current labour analgesia practices are evidence-based; however, such evidence often originates in controlled trials, the results of which may not be readily applicable in the context of day-to-day clinical practice. The objective of this study was to evaluate the effectiveness of and maternal satisfaction with the neuraxial labour analgesia regimen provided at a tertiary care teaching hospital.

METHODS

All women with a viable pregnancy who requested neuraxial analgesia for labour during November 2011 at our institution were approached to participate in this prospective study. Patients were managed as per departmental routine based on a patient-controlled epidural analgesia regimen with a maintenance solution of 0.0625% bupivacaine and fentanyl 2 μg·mL(-1). Demographic and obstetric data, characteristics of the neuraxial analgesia, pain scores, side effects, and complications were recorded. After delivery, patients completed a satisfaction questionnaire.

RESULTS

All 332 eligible women were approached, and 294 completed the study. Most women received epidural analgesia and considered its placement comfortable. A large number of women reported having experienced pain during the first or second stages of labour (38% and 26%, respectively). Although 24.4% of women required top-ups both by nurses and physicians, adjustment in the local anesthetic maintenance concentration was made in only 7.8% of the cases. Most women (92%) were satisfied with the quality of analgesia. Unintentional dural puncture occurred in three (1%) cases, and there were no cases of intravascular catheter insertion or systemic local anesthetic toxicity. Overweight women (body mass index 25-30 kg·m(-2)) (adjusted odds ratio [AOR] = 2.56; 95% confidence interval [CI]: 1.1 to 5.97), those undergoing induced labour (AOR = 2.4; 95% CI: 1.2 to 5.2), and those requiring top-ups by the anesthesiologist (AOR = 5.08; 95% CI: 2.31 to 11.11) were associated with more dissatisfaction with pain control during the first stage of labour.

CONCLUSION

Although our technique with dilute local anesthetic-opioid infusion was considered effective in previous randomized clinical trials, it did not provide sufficient labour analgesia for a large proportion of women. Nevertheless, most women were satisfied with their pain management and childbirth experience. Strategies to individualize care for labour and delivery should be readily available while providing labour analgesia.

摘要

目的

目前的分娩镇痛实践是基于证据的;然而,这些证据往往源自对照试验,其结果可能不易适用于日常临床实践。本研究的目的是评估在一所三级教学医院提供的椎管内分娩镇痛方案的效果和产妇满意度。

方法

在我们医院,2011 年 11 月期间要求接受椎管内分娩镇痛的所有有活力妊娠的妇女都被邀请参加这项前瞻性研究。根据部门常规,根据患者自控硬膜外镇痛方案管理患者,维持溶液为 0.0625%布比卡因和芬太尼 2μg·mL(-1)。记录人口统计学和产科数据、椎管内镇痛的特征、疼痛评分、副作用和并发症。分娩后,患者完成满意度问卷调查。

结果

所有 332 名符合条件的妇女均被邀请,294 名完成了研究。大多数妇女接受了硬膜外镇痛,并认为其放置舒适。许多妇女报告在第一产程或第二产程期间经历了疼痛(分别为 38%和 26%)。尽管有 24.4%的妇女需要护士和医生都进行追加剂量,但只有 7.8%的情况下调整了局部麻醉维持浓度。大多数妇女(92%)对镇痛质量满意。3 例(1%)发生意外硬脊膜穿刺,无血管内导管插入或全身局部麻醉毒性病例。超重妇女(体重指数 25-30kg·m(-2))(调整后的优势比 [AOR] = 2.56;95%置信区间 [CI]:1.1 至 5.97)、接受诱导分娩的妇女(AOR = 2.4;95% CI:1.2 至 5.2)和需要麻醉师追加剂量的妇女(AOR = 5.08;95% CI:2.31 至 11.11)与第一产程疼痛控制不满意相关。

结论

尽管我们使用稀释局部麻醉药-阿片类药物输注的技术在以前的随机临床试验中被认为是有效的,但它并不能为大多数妇女提供足够的分娩镇痛。然而,大多数妇女对她们的疼痛管理和分娩经历感到满意。在提供分娩镇痛时,应随时提供个性化的分娩和分娩护理策略。

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