来自阿根廷患有猪圆环病毒相关疾病的猪的2型猪圆环病毒的基因特征分析。

Genetic characterization of porcine circovirus type 2 from pigs with porcine circovirus associated diseases in Argentina.

作者信息

Pereda Ariel, Piñeyro Pablo, Bratanich Ana, Quiroga María Alejandra, Bucafusco Danilo, Craig María Isabel, Cappuccio Javier, Machuca Mariana, Rimondi Agustina, Dibárbora Marina, Sanguinetti Hector Ramón, Perfumo Carlos Juan

机构信息

Laboratorio Aves y Porcinos, Instituto de Virologia CICVyA, Instituto Nacional de Tecnologia Agropecuaria (INTA), CC25, 1712 Castelar, Buenos Aires, Argentina.

出版信息

ISRN Vet Sci. 2011 May 30;2011:560905. doi: 10.5402/2011/560905. Print 2011.

DOI:10.5402/2011/560905

PMID:23738099

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3658546/

Abstract

Porcine circovirus type 2 (PCV-2) has been associated with syndromes grouped by the term porcine circovirus associated diseases (PCVAD). The PCV-2 isolates have been grouped into two major groups or genotypes according to their nucleotide sequence of whole genomes and/or ORF-2: PCV-2b, which have, in turn, been subdivided into three clusters (1A-1C), and PCV-2a, which has been subdivided into five clusters (2A-2E). In the present study, we obtained 16 sequences of PCV-2 from different farms from 2003 to 2008, from animals with confirmatory diagnosis of PCVAD. Since results showed an identity of 99.8% among them, they were grouped within a common cluster 1A-B. This preliminary study suggests a stable circulation of PCV-2b among the Argentinean pig population.

摘要

猪圆环病毒2型（PCV - 2）与统称为猪圆环病毒相关疾病（PCVAD）的一系列综合征有关。根据全基因组和/或ORF - 2的核苷酸序列，PCV - 2分离株已被分为两个主要组或基因型：PCV - 2b，又可细分为三个簇（1A - 1C），以及PCV - 2a，可细分为五个簇（2A - 2E）。在本研究中，我们从2003年至2008年期间不同猪场确诊患有PCVAD的动物中获得了16个PCV - 2序列。由于结果显示它们之间的同一性为99.8%，因此它们被归为一个共同的1A - B簇。这项初步研究表明PCV - 2b在阿根廷猪群中稳定传播。