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中枢神经系统原发性血管炎:来自哥伦比亚单一中心的三例报告。

Primary angiitis of the central nervous system: a report of three cases from a single colombian center.

作者信息

Coronel-Restrepo Nicolás, Bonilla-Abadía Fabio, Cortes Omar A, Izquierdo Jorge H, Shinchi Alberto M, Bravo Juan C, Tobón Gabriel J, Cañas Carlos A

机构信息

Internal Medicine Unit, Fundación Valle del Lili, CES University, Cali, Colombia.

出版信息

Case Rep Neurol Med. 2013;2013:940438. doi: 10.1155/2013/940438. Epub 2013 May 8.

Abstract

The primary angiitis of the central nervous system (PACNS) is an entity with a very low incidence and prevalence. It is not clear why the inflammatory process of this entity is limited to the cerebral vasculature without systemic manifestations. Its clinical manifestations are very heterogeneous and make clinical diagnosis difficult. In most cases, a brain biopsy is required. Only the clinical suspicion and the ability to recognize the possible clinical and imagenological patterns of presentation make an accurate diagnosis possible. The vast majority of the treatment recommendations are given by series of case reports. The following paper described the clinical, imagenological, and histopathological characteristics of three Colombian patients with PACNS. The strategic therapeutic used in shown.

摘要

中枢神经系统原发性血管炎(PACNS)是一种发病率和患病率极低的疾病。目前尚不清楚为何该疾病的炎症过程局限于脑血管系统而无全身表现。其临床表现非常多样化,导致临床诊断困难。在大多数情况下,需要进行脑活检。只有临床怀疑以及识别可能的临床和影像学表现模式的能力才能实现准确诊断。绝大多数治疗建议来自一系列病例报告。以下论文描述了三名患有PACNS的哥伦比亚患者的临床、影像学和组织病理学特征。展示了所采用的策略性治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af7d/3664475/c6c68a1f24cc/CRIM.NM2013-940438.001.jpg

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