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椎体成形术后无症状性骨水泥肺栓塞:病例报告及文献复习

Asymptomatic bone cement pulmonary embolism after vertebroplasty: case report and literature review.

作者信息

Geraci Girolamo, Lo Iacono Giorgio, Lo Nigro Chiara, Cannizzaro Fabio, Cajozzo Massimo, Modica Giuseppe

机构信息

Section of General and Thoracic Surgery, University of Palermo, Via Liborio, Giuffrè 5, 90124 Palermo, Italy.

出版信息

Case Rep Surg. 2013;2013:591432. doi: 10.1155/2013/591432. Epub 2013 May 7.

Abstract

Introduction. Acrylic cement pulmonary embolism is a potentially serious complication following vertebroplasty. Case Report. A 70-year-old male patient was treated with percutaneous vertebroplasty for osteoporotic nontraumatic vertebral collapse of L5-S1. Asymptomatic pulmonary cement embolism was detected on routine postoperative chest radiogram and the patient was treated with enoxaparin, amoxicillin, and dexamethasone. At the followup CT scan no further migration of any cement material was reported; and the course was uneventful. Discussion. The frequency of local leakage of bone cement is relatively high (about 80-90%), moreover, the rate of cement leakage into the perivertebral veins (seen in up to 24% of vertebral bodies treated) with consequent pulmonary cement embolism varies from 4.6 to 6.8% (up to 26% in radiologic studies); the risk of embolism is increased with the liquid consistency of the cement and with the treatment of some malignant lesions. Patients may remain asymptomatic and develop no known long-term sequelae. Conclusions. Our ancedotal case illustrates the need for close monitoring of patients undergoing percutaneous vertebroplasty and emphasizes the importance of prompt and correct diagnosis and treatment, even if actually there is no agreement regarding the therapeutic strategy.

摘要

引言。骨水泥肺栓塞是椎体成形术后一种潜在的严重并发症。病例报告。一名70岁男性患者因L5-S1骨质疏松性非创伤性椎体塌陷接受经皮椎体成形术治疗。术后常规胸部X线片发现无症状性肺骨水泥栓塞,患者接受依诺肝素、阿莫西林和地塞米松治疗。在随访CT扫描中,未报告任何骨水泥材料有进一步迁移;病程平稳。讨论。骨水泥局部渗漏的发生率相对较高(约80-90%),此外,骨水泥漏入椎旁静脉(在高达24%的接受治疗的椎体中可见)并随之发生肺骨水泥栓塞的发生率在4.6%至6.8%之间变化(在放射学研究中高达26%);骨水泥的液体稠度以及某些恶性病变的治疗会增加栓塞风险。患者可能无症状,也不会出现已知的长期后遗症。结论。我们的个案表明,对接受经皮椎体成形术的患者需要密切监测,并强调及时、正确诊断和治疗的重要性,即使在治疗策略上实际上尚无共识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6964/3662203/5cd3d4c83dc2/CRIM.SURGERY2013-591432.001.jpg

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