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听神经病患者的掩蔽效应——可能与正常外毛细胞功能引起的抑制机制有关。

Masking effects in patients with auditory neuropathy-possible involvement of suppression mechanism caused by normal outer hair cell function.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.

出版信息

Otol Neurotol. 2013 Jul;34(5):868-76. doi: 10.1097/MAO.0b013e318292fcb3.

DOI:10.1097/MAO.0b013e318292fcb3
PMID:23739557
Abstract

OBJECTIVE

Variations in the effects of masking noise were evaluated in different pathologies of sensorineural hearing loss.

STUDY DESIGN

Retrospective chart review.

SETTING

Tertiary referral center.

PATIENTS

Fifty-five ears of 30 patients with sensorineural hearing loss who underwent noise audiometry in the Department of Otolaryngology-Head and Neck Surgery, Tohoku University Hospital, since 2010, because of complaints of hearing difficulty in noisy environments.

MAIN OUTCOME MEASURES

Masked threshold for narrow band and white noise.

RESULTS AND DISCUSSION

Masking effects in patients with auditory neuropathy were significantly larger than those in patients with other types of hearing losses. Masking effects of broad band white noise were greater than those of narrow band noise. Masking effects could be observed for white noise even in the elevated unmasked threshold region, where little contribution of excitatory masking effect would be expected. The present findings support the idea that the suppression mechanism caused by normal outer hair cell function is important in the masking phenomenon in patients with auditory neuropathy.

摘要

目的

评估不同感音神经性听力损失病变中掩蔽噪声的影响变化。

研究设计

回顾性图表审查。

设置

三级转诊中心。

患者

2010 年以来,因在嘈杂环境中听力困难而在东北大学医院耳鼻喉科接受噪声测听的 30 名感音神经性听力损失患者的 55 耳。

主要观察指标

窄带和白噪声的掩蔽阈值。

结果与讨论

听神经病患者的掩蔽效应明显大于其他类型听力损失患者。宽带白噪声的掩蔽效应大于窄带噪声。即使在未掩蔽阈值升高的区域,也可以观察到白噪声的掩蔽效应,在该区域,不应期望兴奋性掩蔽效应有很大贡献。本研究结果支持这样一种观点,即正常外毛细胞功能引起的抑制机制在听神经病患者的掩蔽现象中很重要。

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Masking effects in patients with auditory neuropathy-possible involvement of suppression mechanism caused by normal outer hair cell function.听神经病患者的掩蔽效应——可能与正常外毛细胞功能引起的抑制机制有关。
Otol Neurotol. 2013 Jul;34(5):868-76. doi: 10.1097/MAO.0b013e318292fcb3.
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