Dumville Jo C, Deshpande Sohan, O'Meara Susan, Speak Katharine
Department of Nursing,Midwifery and Social Work, University of Manchester, Manchester,UK.
Cochrane Database Syst Rev. 2013 Jun 6;2013(6):CD009111. doi: 10.1002/14651858.CD009111.pub3.
Foot ulcers in people with diabetes are a prevalent and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many different types to choose from. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use.
The review aimed to evaluate the effects of foam wound dressings on the healing of foot ulcers in people with diabetes.
For this first update we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL in April 2013. There were no restrictions based on language or date of publication.
Published or unpublished randomised controlled trials (RCTs) that evaluated the effects on ulcer healing of one or more foam wound dressings in the treatment of foot ulcers in people with diabetes.
Two review authors independently performed study selection, risk of bias assessment and data extraction.
We included six studies (157 participants) in this review. Meta analysis of two studies indicated that foam dressings do not promote the healing of diabetic foot ulcers compared with basic wound contact dressings (RR 2.03, 95%CI 0.91 to 4.55). Pooled data from two studies comparing foam and alginate dressing found no statistically significant difference in ulcer healing (RR 1.50, 95% CI 0.92 to 2.44). There was no statistically significant difference in the number of diabetic foot ulcers healed when foam dressings were compared with hydrocolloid (matrix) dressings. All included studies were small and/or had limited follow-up times.
AUTHORS' CONCLUSIONS: Currently there is no research evidence to suggest that foam wound dressings are more effective in healing foot ulcers in people with diabetes than other types of dressing however all trials in this field are very small. Decision makers may wish to consider aspects such as dressing cost and the wound management properties offered by each dressing type e.g. exudate management.
糖尿病患者足部溃疡是一个普遍且严重的全球健康问题。敷料是溃疡治疗的关键部分,临床医生和患者有多种不同类型可供选择。需要一份清晰且最新的现有证据概述,以促进关于敷料使用的决策。
本综述旨在评估泡沫伤口敷料对糖尿病患者足部溃疡愈合的影响。
对于本次首次更新,我们于2013年4月检索了以下数据库:Cochrane伤口小组专业注册库;Cochrane对照试验中心注册库(CENTRAL)(Cochrane图书馆);Ovid MEDLINE;Ovid MEDLINE(在研及其他未索引引文);Ovid EMBASE;以及EBSCO CINAHL。没有基于语言或出版日期的限制。
评估一种或多种泡沫伤口敷料治疗糖尿病患者足部溃疡对溃疡愈合影响的已发表或未发表的随机对照试验(RCT)。
两位综述作者独立进行研究选择、偏倚风险评估和数据提取。
本综述纳入了6项研究(157名参与者)。两项研究的荟萃分析表明,与基本伤口接触敷料相比,泡沫敷料并不能促进糖尿病足溃疡的愈合(风险比2.03,95%置信区间0.91至4.55)。两项比较泡沫敷料和藻酸盐敷料的研究汇总数据显示,溃疡愈合方面无统计学显著差异(风险比1.50,95%置信区间0.92至2.�4)。将泡沫敷料与水胶体(基质)敷料比较时,愈合的糖尿病足溃疡数量无统计学显著差异。所有纳入研究规模较小和/或随访时间有限。
目前没有研究证据表明泡沫伤口敷料在治疗糖尿病患者足部溃疡方面比其他类型敷料更有效,然而该领域的所有试验规模都非常小。决策者可能希望考虑诸如敷料成本以及每种敷料类型所提供的伤口管理特性(如渗出液管理)等方面。