Bergh A, Damber J E, Widmark A
Department of Anatomy, University of Umeå, Sweden.
J Reprod Fertil. 1990 May;89(1):23-31. doi: 10.1530/jrf.0.0890023.
Adult male rats were injected with different doses of hCG, or with 2.5 micrograms ovine LH subcutaneously, and other rats were mated with oestrous females. The animals were examined 4 h after treatments. Treatment with hCG resulted in a dose-dependent increase in leucocyte concentration in testicular blood vessels and in the number of blood vessels which could be labelled with intravenously injected carbon particles. Carbon leakage was not observed in control testes. Treatment with a low dose of ovine LH or inducing an endogenous LH peak by mating also resulted in leucocyte accumulation and vascular leakage of carbon in the testis. The magnitude of the response was considerably lower than after high doses of hCG. The physiological relevance of the discrete response observed after physiological LH stimulation is unknown but LH-induced changes in testicular microcirculation could be of interest for the understanding of the physiology and pathophysiology of the testis.
成年雄性大鼠皮下注射不同剂量的人绒毛膜促性腺激素（hCG）或2.5微克的绵羊促黄体生成素（LH），其他大鼠与处于发情期的雌性大鼠交配。处理后4小时对动物进行检查。hCG处理导致睾丸血管中白细胞浓度呈剂量依赖性增加，且可被静脉注射的碳颗粒标记的血管数量增加。在对照睾丸中未观察到碳泄漏。低剂量绵羊LH处理或通过交配诱导内源性LH峰值也导致睾丸中白细胞积聚和碳的血管渗漏。反应程度明显低于高剂量hCG处理后。生理LH刺激后观察到的离散反应的生理相关性尚不清楚，但LH诱导的睾丸微循环变化可能有助于理解睾丸的生理学和病理生理学。
