Bergh A, Damber J E
Department of Anatomy and Pathology, University of Umeå, Sweden.
J Reprod Fertil. 1987 Jul;80(2):623-7. doi: 10.1530/jrf.0.0800623.
Treatment with hCG results in an increase in venular permeability in the rat testis. This change in vascular permeability can be detected by the carbon-labelling technique, by measurement of the volume of interstitial fluid and by quantification of the leucocyte migration into the interstitial space. Carbon-labelling, interstitial fluid volume and leucocyte migration were all reduced in rats treated with hCG+ terbutaline compared to the values in animals given hCG only. However, terbutaline treatment did not influence the hCG-induced increase in testosterone secretion. These observations suggest that the hCG-induced increase in vascular permeability in the testis can be reduced by a beta-adrenergic agonist.
用绒毛膜促性腺激素（hCG）治疗会导致大鼠睾丸小静脉通透性增加。这种血管通透性的变化可以通过碳标记技术、测量间质液体积以及对迁移到间质空间的白细胞进行定量来检测。与仅给予hCG的动物相比，用hCG + 特布他林治疗的大鼠的碳标记、间质液体积和白细胞迁移均减少。然而，特布他林治疗并不影响hCG诱导的睾酮分泌增加。这些观察结果表明，β-肾上腺素能激动剂可以降低hCG诱导的睾丸血管通透性增加。
