Radiation Oncology Unit, University of Turin, S. Luigi Hospital, Orbassano, Italy.
Ann Thorac Med. 2013 Apr;8(2):121-3. doi: 10.4103/1817-1737.109834.
Ewing's sarcomas and peripheral primitive neuroectodermal tumors (ES/PNETs) are high grade malignant neoplasms. These malignancies are characterized by a chromosome 22 rearrangement, arise from bone or soft tissue, predominantly affect children and young adults, and are grouped in the Ewing family of tumors. Multimodality treatment programs are the treatment of choice. Primary localization of ES/PNET in the mediastinum is extremely rare. We describe a case of ES/PNET presenting as a mediastinal mass with tracheal compression and initial signs of superior vena cava in a 66-year-old woman.
尤因氏肉瘤和外周原始神经外胚层肿瘤(ES/PNET)是高度恶性肿瘤。这些恶性肿瘤的特征是 22 号染色体重排,起源于骨或软组织,主要影响儿童和青少年,并被归为尤因氏肿瘤家族。多模式治疗方案是首选治疗方法。ES/PNET 原发于纵隔极为罕见。我们描述了一例 66 岁女性患者,表现为纵隔肿块伴气管压迫和上腔静脉初始受压的症状。