Homeida A M, Khalafalla A E
Department of Veterinary Medicine, Pharmacology and Toxicology, University of Khartoum, Sudan.
J Reprod Fertil. 1990 May;89(1):347-50. doi: 10.1530/jrf.0.0890347.
Oxytocin at a dose of 100 i.u. injected subcutaneously (s.c.) daily to goats between Days 3 and 6 of the oestrous cycle caused a significant increase in testosterone secretion compared with saline-treated animals. An oxytocin antagonist (0.2 micrograms/kg) injected intra-arterially between Days 12 and 18 of the oestrous cycle or simultaneously with oxytocin between Days 3 and 6 blocked the increased release of testosterone and occurrence of oestrus. It is suggested that oxytocin-induced oestrus may occur via testosterone secretion.
在发情周期的第3至6天，每天给山羊皮下注射100国际单位的催产素，与注射生理盐水的动物相比，可导致睾酮分泌显著增加。在发情周期的第12至18天动脉内注射催产素拮抗剂（0.2微克/千克），或在第3至6天与催产素同时注射，可阻断睾酮释放增加和发情的发生。提示催产素诱导的发情可能通过睾酮分泌发生。
