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重组羊干扰素处理山羊(Capra hircus)后黄体溶解延迟及睾酮分泌受抑制

Delayed luteolysis and suppression of testosterone secretion after recombinant ovine interferon treatment in goats (Capra hircus).

作者信息

Homeida A M, al-Afaleq A I

机构信息

College of Veterinary Medicine and Animal Resources, King Faisal University, Al-Ahsa, Saudi Arabia.

出版信息

J Reprod Fertil. 1994 Nov;102(2):301-4. doi: 10.1530/jrf.0.1020301.

DOI:10.1530/jrf.0.1020301
PMID:7861381
Abstract

Oxytocin at a dose of 100 iu injected s.c. daily into goats (Capra hircus) between day 3 and day 6 of the oestrous cycle caused a significant increase in testosterone secretion and luteolysis compared with saline-treated animals. Intrauterine administration of recombinant ovine interferon tau (80, 160 or 320 micrograms day-1) between days 12 and 18 of the oestrous cycle, or concomitantly (80 micrograms day-1) with oxytocin between day 3 and day 7, delayed luteolysis and blocked the increased release of testosterone. It is suggested that recombinant ovine interferon tau can act as an antiluteolytic agent in goats.

摘要

在发情周期的第3天至第6天,每天给山羊(Capra hircus)皮下注射100国际单位的催产素,与生理盐水处理的动物相比,可导致睾酮分泌显著增加和黄体溶解。在发情周期的第12天至第18天,或在第3天至第7天与催产素同时(每天80微克)子宫内给予重组羊干扰素τ(80、160或320微克/天),可延迟黄体溶解并阻止睾酮释放增加。提示重组羊干扰素τ可作为山羊的抗黄体溶解剂。

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