Sakamoto W, Kishimoto T, Yamamoto K, Sugimoto T, Senju M, Iimori H, Kanazawa T, Wada S, Maekawa M
Department of Urology, Osaka City University of Medical School, Japan.
Nihon Hinyokika Gakkai Zasshi. 1990 Apr;81(4):589-92. doi: 10.5980/jpnjurol1989.81.589.
Extracorporeal shook wave lithotripsy (ESWL) was performed for the treatment of 1277 urolithiasis patients at Osaka City University Hospital from July, 1985 to December, 1988. A total of 1788 ESWL treatments were carried out using Dornier HM3 kidney lithotripter. 964 patients (75.5%) underwent only one ESWL treatment, while 313 patients (24.5%) more than two ESWL treatments. We retrospectively examined the factors for requiring more than two ESWL treatments. Not only stone number, size and location, but fragility were considered to be the main causes for requiring more than two ESWL treatments. According to component analysis of ureteral stones, which were hard and resistant to shock wave, calcium apatite content of these stones turned out to be high (p less than 0.001). As for fragility, the residual stones created by ESWL were more difficult to be disintegrated that the nontreated stones of the same size (p less than 0.05). "Fragility" of the stones before shock wave and residual stones after ESWL are considered to be a major problem in ESWL treatment of urinary stones to be solved in the years to come.
1985年7月至1988年12月期间,大阪市立大学医院对1277例尿石症患者进行了体外冲击波碎石术(ESWL)治疗。使用多尼尔HM3型肾脏碎石机共进行了1788次ESWL治疗。964例患者(75.5%)仅接受了一次ESWL治疗,而313例患者(24.5%)接受了两次以上的ESWL治疗。我们回顾性研究了需要接受两次以上ESWL治疗的相关因素。结石的数量、大小、位置以及易碎性均被认为是需要接受两次以上ESWL治疗的主要原因。根据对坚硬且对冲击波有抵抗性的输尿管结石成分分析,结果显示这些结石的磷灰石钙含量较高(p<0.001)。至于易碎性,ESWL产生的残留结石比相同大小的未治疗结石更难被击碎(p<0.05)。结石在冲击波治疗前的“易碎性”以及ESWL后的残留结石被认为是未来几年ESWL治疗尿路结石中需要解决的主要问题。