Bottino G, Menna C
USL n. 35, Ospedale Civile di Giaveno.
Minerva Ginecol. 1990 May;42(5):197-9.
The authors examined 20 patients affected by vaginal candidiasis and evaluated the efficacy and tolerability of treatment with Fluconazole in comparison with Ketoconazole, using two different doses of oral administration: Fluconazole, 150 mg in a single dose; Ketoconazole, 400 mg/die for 5 days. There were no significant differences in results; adverse effects were insignificant and the level of efficacy, which was the same in both cases, was high. In conclusion, both molecules are confirmed to be efficacious, although patients showed a preference for the single dose and for only one day of therapy.
作者检查了20例阴道念珠菌病患者，并比较了氟康唑与酮康唑两种不同口服剂量治疗的疗效和耐受性：氟康唑，单次剂量150mg；酮康唑，每日400mg，连用5天。结果无显著差异；不良反应不明显，两种药物的疗效水平相同且都很高。总之，两种药物均被证实有效，尽管患者更倾向于单次剂量和仅一天的治疗。
